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    Trabd TraB domain containing [ Mus musculus (house mouse) ]

    Gene ID: 67976, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Trabdprovided by MGI
    Official Full Name
    TraB domain containingprovided by MGI
    Primary source
    MGI:MGI:1915226
    See related
    Ensembl:ENSMUSG00000015363 AllianceGenome:MGI:1915226
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5730502D15Rik
    Summary
    Predicted to be involved in mitochondrial fusion. Predicted to be located in mitochondrial outer membrane. Orthologous to human TRABD (TraB domain containing). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in large intestine adult (RPKM 33.4), duodenum adult (RPKM 33.1) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Trabd in Genome Data Viewer
    Location:
    15 E3; 15 44.59 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (88960267..88971278)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (89076064..89087075)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene Mov10 like RISC complex RNA helicase 1 Neighboring gene predicted gene, 23737 Neighboring gene STARR-seq mESC enhancer starr_39456 Neighboring gene STARR-seq mESC enhancer starr_39457 Neighboring gene RIKEN cDNA 1810021B22 gene Neighboring gene pannexin 2 Neighboring gene selenoprotein O Neighboring gene tubulin, gamma complex component 6 Neighboring gene STARR-positive B cell enhancer ABC_E5508 Neighboring gene histone deacetylase 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains. Inoue S, et al. Biochem Biophys Res Commun, 2000 Feb 16. PMID 10679242
    2. Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Apr 30. PMID 15449545
    3. A global genomic transcriptional code associated with CNS-expressed genes. Bailey PJ, et al. Exp Cell Res, 2006 Oct 1. PMID 16919269
    4. Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Harrison SM, et al. Development, 1995 Aug. PMID 7671812
    5. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Gene trapped (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in mitochondrial fusion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    traB domain-containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355617.1 → NP_001342546.1  traB domain-containing protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC113069
      Conserved Domains (1) summary
      cl12050
      Location:14 → 227
      TraB; TraB family

    2. NM_001378756.1 → NP_001365685.1  traB domain-containing protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC113069
      UniProtKB/Swiss-Prot
      Q99JY4, Q9CYF1
      Related
      ENSMUSP00000131228.2, ENSMUST00000165690.2
      Conserved Domains (1) summary
      cd14726
      Location:74 → 272
      TraB_PrgY-like; TraB/PryY confer plasmid-borne pheromone resistance

    3. NM_001378757.1 → NP_001365686.1  traB domain-containing protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC113069
      Conserved Domains (1) summary
      cd14726
      Location:139 → 337
      TraB_PrgY-like; TraB/PryY confer plasmid-borne pheromone resistance

    4. NM_001378758.1 → NP_001365687.1  traB domain-containing protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC113069
      Conserved Domains (1) summary
      cd14726
      Location:139 → 337
      TraB_PrgY-like; TraB/PryY confer plasmid-borne pheromone resistance

    5. NM_026485.2 → NP_080761.2  traB domain-containing protein isoform 1

      See identical proteins and their annotated locations for NP_080761.2

      Status: VALIDATED

      Source sequence(s)
      AB030206, AK146027, BU510197, CX200611
      Consensus CDS
      CCDS49696.1
      UniProtKB/Swiss-Prot
      Q99JY4, Q9CYF1
      Related
      ENSMUSP00000080403.6, ENSMUST00000081702.12
      Conserved Domains (1) summary
      cd14726
      Location:74 → 272
      TraB_PrgY-like; TraB/PryY confer plasmid-borne pheromone resistance

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      88960267..88971278
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99JY4.1 GenPept UniProtKB/Swiss-Prot:Q99JY4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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