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    Wdr36 WD repeat domain 36 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 688637, updated on 27-Nov-2024

    Summary

    Official Symbol
    Wdr36provided by RGD
    Official Full Name
    WD repeat domain 36provided by RGD
    Primary source
    RGD:1586463
    See related
    EnsemblRapid:ENSRNOG00000027355 AllianceGenome:RGD:1586463
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to act upstream of or within regulation of axon extension and retina homeostasis. Predicted to be located in nucleolus. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Human ortholog(s) of this gene implicated in glaucoma and primary open angle glaucoma. Orthologous to human WDR36 (WD repeat domain 36). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 143.6), Spleen (RPKM 127.6) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Wdr36 in Genome Data Viewer
    Location:
    18p12
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (24747812..24783704)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (24473657..24501773)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (25637475..25665801)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene transfer RNA alanine (anticodon AGC) 30 Neighboring gene thymic stromal lymphopoietin Neighboring gene uncharacterized LOC134482926 Neighboring gene calcium/calmodulin-dependent protein kinase IV Neighboring gene uncharacterized LOC120098266

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within regulation of axon extension ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within retina homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ribosomal small subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of Pwp2p-containing subcomplex of 90S preribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of small-subunit processome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    WD repeat-containing protein 36

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001400815.1NP_001387744.1  WD repeat-containing protein 36

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000018
      Related
      ENSRNOP00000036935.7, ENSRNOT00000031530.9

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      24747812..24783704
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063277596.1XP_063133666.1  WD repeat-containing protein 36 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A876
      Related
      ENSRNOP00000066707.3, ENSRNOT00000075283.3

    RNA

    1. XR_010059604.1 RNA Sequence

    2. XR_010059605.1 RNA Sequence