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    PICALM phosphatidylinositol binding clathrin assembly protein [ Homo sapiens (human) ]

    Gene ID: 8301, updated on 3-Dec-2024

    Summary

    Official Symbol
    PICALMprovided by HGNC
    Official Full Name
    phosphatidylinositol binding clathrin assembly proteinprovided by HGNC
    Primary source
    HGNC:HGNC:15514
    See related
    Ensembl:ENSG00000073921 MIM:603025; AllianceGenome:HGNC:15514
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    LAP; CALM; CLTH
    Summary
    This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10;11)(p13;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
    Expression
    Ubiquitous expression in fat (RPKM 64.4), appendix (RPKM 52.9) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See PICALM in Genome Data Viewer
    Location:
    11q14.2
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (85957175..86069860, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (85893875..86006599, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (85668218..85780902, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 83 Neighboring gene adenosylhomocysteinase pseudogene 6 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:85646587-85647178 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr11:85647179-85647769 Neighboring gene solute carrier family 25 member 1 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5371 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:85665736-85666236 Neighboring gene uncharacterized LOC124902730 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:85778772-85779474 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:85779916-85781115 Neighboring gene uncharacterized LOC124902731 Neighboring gene small nucleolar RNA U13

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
    EBI GWAS Catalog
    Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
    EBI GWAS Catalog
    Genome-wide association study of Alzheimer's disease.
    EBI GWAS Catalog
    Genome-wide association study of Tourette's syndrome.
    EBI GWAS Catalog
    Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
    EBI GWAS Catalog
    The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.
    EBI GWAS Catalog

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables 1-phosphatidylinositol binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables SNARE binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables amyloid-beta binding IC
    Inferred by Curator
    more info
     
    enables cadherin binding HDA PubMed 
    enables clathrin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables clathrin heavy chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables clathrin heavy chain binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables low-density lipoprotein particle receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables phosphatidylinositol-4,5-bisphosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphatidylinositol-4,5-bisphosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables small GTPase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables tau protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in amyloid-beta clearance by transcytosis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in amyloid-beta clearance by transcytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in axonogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in clathrin coat assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in clathrin coat assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in clathrin-dependent endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in clathrin-dependent endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in dendrite morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endocytosis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in endosomal transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in hemopoiesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in intracellular iron ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in learning or memory ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in membrane bending IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in multicellular organismal-level iron ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of protein localization to cell surface IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of protein localization to plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of receptor-mediated endocytosis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of Ras protein signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of amyloid precursor protein catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of amyloid-beta formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein-containing complex assembly TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in receptor internalization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in receptor-mediated endocytosis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of amyloid precursor protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    NOT involved_in regulation of amyloid-beta formation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in regulation of endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of protein localization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of vesicle size IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in synaptic vesicle budding from presynaptic endocytic zone membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in synaptic vesicle maturation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in vesicle budding from membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in vesicle cargo loading IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in vesicle-mediated transport TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of clathrin coat of coated pit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in clathrin-coated endocytic vesicle NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in clathrin-coated pit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in clathrin-coated pit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in clathrin-coated pit IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    is_active_in clathrin-coated vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in clathrin-coated vesicle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in early endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endosome to plasma membrane transport vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in extrinsic component of presynaptic endocytic zone membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in intracellular membrane-bounded organelle IDA
    Inferred from Direct Assay
    more info
     
    located_in membrane HDA PubMed 
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in neurofibrillary tangle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with perinuclear region of cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in postsynaptic membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in presynaptic membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in synaptic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in vesicle ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    phosphatidylinositol-binding clathrin assembly protein
    Names
    clathrin assembly lymphoid myeloid leukemia protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_028942.2 RefSeqGene

      Range
      5776..117685
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001008660.3NP_001008660.1  phosphatidylinositol-binding clathrin assembly protein isoform 2

      See identical proteins and their annotated locations for NP_001008660.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon, but has an additional downstream in-frame exon, in the coding region, as compared to variant 1. The encoded isoform 2 thus lacks an internal segment and also has an additional segment, as compared to isoform 1.
      Source sequence(s)
      AP000767
      Consensus CDS
      CCDS31653.1
      UniProtKB/TrEMBL
      B5BU72
      Related
      ENSP00000436958.1, ENST00000532317.5
      Conserved Domains (2) summary
      COG4223
      Location:268366
      COG4223; Uncharacterized conserved protein [Function unknown]
      pfam07651
      Location:24282
      ANTH; ANTH domain
    2. NM_001206946.2NP_001193875.1  phosphatidylinositol-binding clathrin assembly protein isoform 3

      See identical proteins and their annotated locations for NP_001193875.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) has an alternate splice site in the coding sequence, compared to variant 1. The resulting isoform (3) lacks an internal segment, compared to isoform 1.
      Source sequence(s)
      AP000767
      Consensus CDS
      CCDS55784.1
      UniProtKB/TrEMBL
      A8K5U9
      Related
      ENSP00000433846.1, ENST00000526033.5
      Conserved Domains (1) summary
      pfam07651
      Location:24282
      ANTH; ANTH domain
    3. NM_001206947.2NP_001193876.1  phosphatidylinositol-binding clathrin assembly protein isoform 4

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) has an alternate 5' exon, resulting in a downstream AUG start codon, and lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (4) has a shorter N-terminus and lacks an internal segment, compared to isoform 1.
      Source sequence(s)
      AK128786, AK300275, BC073961, CA415536, DC300074
      Consensus CDS
      CCDS55783.1
      UniProtKB/TrEMBL
      B5BU72
      Related
      ENSP00000434884.1, ENST00000528398.5
      Conserved Domains (2) summary
      pfam07651
      Location:1231
      ANTH; ANTH domain
      pfam08287
      Location:214293
      DASH_Spc19; Spc19
    4. NM_001411034.1NP_001397963.1  phosphatidylinositol-binding clathrin assembly protein isoform 5

      Status: REVIEWED

      Source sequence(s)
      AP000767
      Consensus CDS
      CCDS91570.1
      UniProtKB/TrEMBL
      A8K5U9
      Related
      ENSP00000348718.5, ENST00000356360.9
    5. NM_007166.4NP_009097.2  phosphatidylinositol-binding clathrin assembly protein isoform 1

      See identical proteins and their annotated locations for NP_009097.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AP000767
      Consensus CDS
      CCDS8272.1
      UniProtKB/Swiss-Prot
      B4DTM3, E9PN05, F8VPG7, O60700, Q13492, Q4LE54, Q6GMQ6, Q86XZ9
      UniProtKB/TrEMBL
      A8K5U9
      Related
      ENSP00000377015.3, ENST00000393346.8
      Conserved Domains (2) summary
      pfam07651
      Location:19282
      ANTH; ANTH domain
      pfam08287
      Location:265344
      DASH_Spc19; Spc19

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      85957175..86069860 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047427666.1XP_047283622.1  phosphatidylinositol-binding clathrin assembly protein isoform X23

      UniProtKB/TrEMBL
      B5BU72
    2. XM_047427660.1XP_047283616.1  phosphatidylinositol-binding clathrin assembly protein isoform X8

      UniProtKB/TrEMBL
      A8K5U9
    3. XM_047427669.1XP_047283625.1  phosphatidylinositol-binding clathrin assembly protein isoform X26

      UniProtKB/TrEMBL
      B5BU72
    4. XM_047427667.1XP_047283623.1  phosphatidylinositol-binding clathrin assembly protein isoform X24

      UniProtKB/TrEMBL
      B5BU72
    5. XM_047427665.1XP_047283621.1  phosphatidylinositol-binding clathrin assembly protein isoform X21

      UniProtKB/TrEMBL
      B5BU72
    6. XM_017018388.3XP_016873877.1  phosphatidylinositol-binding clathrin assembly protein isoform X20

      UniProtKB/TrEMBL
      B5BU72
    7. XM_047427668.1XP_047283624.1  phosphatidylinositol-binding clathrin assembly protein isoform X25

      UniProtKB/TrEMBL
      B5BU72
    8. XM_017018387.3XP_016873876.1  phosphatidylinositol-binding clathrin assembly protein isoform X19

      UniProtKB/TrEMBL
      B5BU72
    9. XM_017018384.3XP_016873873.1  phosphatidylinositol-binding clathrin assembly protein isoform X14

      UniProtKB/TrEMBL
      B5BU72
      Conserved Domains (2) summary
      pfam07651
      Location:19282
      ANTH; ANTH domain
      pfam08287
      Location:265344
      DASH_Spc19; Spc19
    10. XM_005274336.4XP_005274393.1  phosphatidylinositol-binding clathrin assembly protein isoform X12

      UniProtKB/TrEMBL
      B5BU72
      Conserved Domains (2) summary
      pfam07651
      Location:19282
      ANTH; ANTH domain
      pfam08287
      Location:265344
      DASH_Spc19; Spc19
    11. XM_005274340.4XP_005274397.1  phosphatidylinositol-binding clathrin assembly protein isoform X22

      UniProtKB/TrEMBL
      B5BU72
      Conserved Domains (2) summary
      pfam07651
      Location:19282
      ANTH; ANTH domain
      pfam08287
      Location:265344
      DASH_Spc19; Spc19
    12. XM_017018386.3XP_016873875.1  phosphatidylinositol-binding clathrin assembly protein isoform X18

      UniProtKB/TrEMBL
      B5BU72
    13. XM_017018383.3XP_016873872.1  phosphatidylinositol-binding clathrin assembly protein isoform X13

      UniProtKB/TrEMBL
      B5BU72
      Conserved Domains (2) summary
      pfam07651
      Location:19282
      ANTH; ANTH domain
      pfam08287
      Location:265344
      DASH_Spc19; Spc19
    14. XM_047427662.1XP_047283618.1  phosphatidylinositol-binding clathrin assembly protein isoform X11

      UniProtKB/TrEMBL
      A8K5U9
    15. XM_047427659.1XP_047283615.1  phosphatidylinositol-binding clathrin assembly protein isoform X7

      UniProtKB/TrEMBL
      A8K5U9
    16. XM_017018381.3XP_016873870.1  phosphatidylinositol-binding clathrin assembly protein isoform X5

      UniProtKB/TrEMBL
      A8K5U9
    17. XM_047427663.1XP_047283619.1  phosphatidylinositol-binding clathrin assembly protein isoform X17

      UniProtKB/TrEMBL
      A8K5U9
    18. XM_047427661.1XP_047283617.1  phosphatidylinositol-binding clathrin assembly protein isoform X10

      UniProtKB/TrEMBL
      A8K5U9
    19. XM_024448700.2XP_024304468.1  phosphatidylinositol-binding clathrin assembly protein isoform X4

      UniProtKB/TrEMBL
      A8K5U9
      Conserved Domains (2) summary
      COG4223
      Location:268366
      COG4223; Uncharacterized conserved protein [Function unknown]
      pfam07651
      Location:24282
      ANTH; ANTH domain
    20. XM_017018385.3XP_016873874.1  phosphatidylinositol-binding clathrin assembly protein isoform X16

      UniProtKB/TrEMBL
      A8K5U9
    21. XM_005274334.4XP_005274391.1  phosphatidylinositol-binding clathrin assembly protein isoform X9

      UniProtKB/TrEMBL
      A8K5U9
      Conserved Domains (2) summary
      pfam07651
      Location:19282
      ANTH; ANTH domain
      pfam08287
      Location:265344
      DASH_Spc19; Spc19
    22. XM_005274329.5XP_005274386.1  phosphatidylinositol-binding clathrin assembly protein isoform X6

      UniProtKB/TrEMBL
      A8K5U9
      Conserved Domains (1) summary
      cd16985
      Location:22138
      ANTH_N_AP180; ANTH (AP180 N-Terminal Homology) domain, N-terminal region, of adaptor protein 180 (AP180) subfamily
    23. XM_005274328.4XP_005274385.1  phosphatidylinositol-binding clathrin assembly protein isoform X3

      UniProtKB/TrEMBL
      A8K5U9
      Conserved Domains (2) summary
      pfam07651
      Location:19282
      ANTH; ANTH domain
      pfam08287
      Location:265344
      DASH_Spc19; Spc19
    24. XM_005274337.4XP_005274394.1  phosphatidylinositol-binding clathrin assembly protein isoform X15

      UniProtKB/TrEMBL
      A8K5U9
      Conserved Domains (2) summary
      pfam07651
      Location:19282
      ANTH; ANTH domain
      pfam08287
      Location:265344
      DASH_Spc19; Spc19
    25. XM_005274326.4XP_005274383.1  phosphatidylinositol-binding clathrin assembly protein isoform X2

      See identical proteins and their annotated locations for XP_005274383.1

      UniProtKB/TrEMBL
      A8K5U9
      Conserved Domains (2) summary
      pfam07651
      Location:19282
      ANTH; ANTH domain
      pfam08287
      Location:265344
      DASH_Spc19; Spc19
    26. XM_005274322.4XP_005274379.1  phosphatidylinositol-binding clathrin assembly protein isoform X1

      UniProtKB/TrEMBL
      A8K5U9
      Conserved Domains (3) summary
      pfam07651
      Location:19282
      ANTH; ANTH domain
      pfam08287
      Location:265344
      DASH_Spc19; Spc19
      pfam11029
      Location:578657
      DAZAP2; DAZ associated protein 2 (DAZAP2)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      85893875..86006599 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054370120.1XP_054226095.1  phosphatidylinositol-binding clathrin assembly protein isoform X23

      UniProtKB/TrEMBL
      B5BU72
    2. XM_054370104.1XP_054226079.1  phosphatidylinositol-binding clathrin assembly protein isoform X8

      UniProtKB/TrEMBL
      A8K5U9
    3. XM_054370123.1XP_054226098.1  phosphatidylinositol-binding clathrin assembly protein isoform X26

      UniProtKB/TrEMBL
      B5BU72
    4. XM_054370121.1XP_054226096.1  phosphatidylinositol-binding clathrin assembly protein isoform X24

      UniProtKB/TrEMBL
      B5BU72
    5. XM_054370118.1XP_054226093.1  phosphatidylinositol-binding clathrin assembly protein isoform X21

      UniProtKB/TrEMBL
      B5BU72
    6. XM_054370117.1XP_054226092.1  phosphatidylinositol-binding clathrin assembly protein isoform X20

      UniProtKB/TrEMBL
      B5BU72
    7. XM_054370110.1XP_054226085.1  phosphatidylinositol-binding clathrin assembly protein isoform X27

      UniProtKB/TrEMBL
      B5BU72
    8. XM_054370122.1XP_054226097.1  phosphatidylinositol-binding clathrin assembly protein isoform X25

      UniProtKB/TrEMBL
      B5BU72
    9. XM_054370116.1XP_054226091.1  phosphatidylinositol-binding clathrin assembly protein isoform X19

      UniProtKB/TrEMBL
      B5BU72
    10. XM_054370111.1XP_054226086.1  phosphatidylinositol-binding clathrin assembly protein isoform X14

      UniProtKB/TrEMBL
      B5BU72
    11. XM_054370108.1XP_054226083.1  phosphatidylinositol-binding clathrin assembly protein isoform X12

      UniProtKB/TrEMBL
      B5BU72
    12. XM_054370119.1XP_054226094.1  phosphatidylinositol-binding clathrin assembly protein isoform X22

      UniProtKB/TrEMBL
      B5BU72
    13. XM_054370115.1XP_054226090.1  phosphatidylinositol-binding clathrin assembly protein isoform X18

      UniProtKB/TrEMBL
      B5BU72
    14. XM_054370109.1XP_054226084.1  phosphatidylinositol-binding clathrin assembly protein isoform X13

      UniProtKB/TrEMBL
      B5BU72
    15. XM_054370107.1XP_054226082.1  phosphatidylinositol-binding clathrin assembly protein isoform X11

      UniProtKB/TrEMBL
      A8K5U9
    16. XM_054370103.1XP_054226078.1  phosphatidylinositol-binding clathrin assembly protein isoform X7

      UniProtKB/TrEMBL
      A8K5U9
    17. XM_054370101.1XP_054226076.1  phosphatidylinositol-binding clathrin assembly protein isoform X5

      UniProtKB/TrEMBL
      A8K5U9
    18. XM_054370114.1XP_054226089.1  phosphatidylinositol-binding clathrin assembly protein isoform X17

      UniProtKB/TrEMBL
      A8K5U9
    19. XM_054370106.1XP_054226081.1  phosphatidylinositol-binding clathrin assembly protein isoform X10

      UniProtKB/TrEMBL
      A8K5U9
    20. XM_054370100.1XP_054226075.1  phosphatidylinositol-binding clathrin assembly protein isoform X4

      UniProtKB/TrEMBL
      A8K5U9
    21. XM_054370113.1XP_054226088.1  phosphatidylinositol-binding clathrin assembly protein isoform X16

      UniProtKB/TrEMBL
      A8K5U9
    22. XM_054370105.1XP_054226080.1  phosphatidylinositol-binding clathrin assembly protein isoform X9

      UniProtKB/TrEMBL
      A8K5U9
    23. XM_054370102.1XP_054226077.1  phosphatidylinositol-binding clathrin assembly protein isoform X6

      UniProtKB/TrEMBL
      A8K5U9
    24. XM_054370099.1XP_054226074.1  phosphatidylinositol-binding clathrin assembly protein isoform X3

      UniProtKB/TrEMBL
      A8K5U9
    25. XM_054370112.1XP_054226087.1  phosphatidylinositol-binding clathrin assembly protein isoform X15

      UniProtKB/TrEMBL
      A8K5U9
    26. XM_054370098.1XP_054226073.1  phosphatidylinositol-binding clathrin assembly protein isoform X2

      UniProtKB/TrEMBL
      A8K5U9
    27. XM_054370097.1XP_054226072.1  phosphatidylinositol-binding clathrin assembly protein isoform X1

      UniProtKB/TrEMBL
      A8K5U9