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    LOC105376689 translation initiation factor IF-2 [ Homo sapiens (human) ]

    Gene ID: 105376689, updated on 17-Sep-2024

    Summary

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    Gene symbol
    LOC105376689
    Gene description
    translation initiation factor IF-2
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Broad expression in testis (RPKM 1.0), spleen (RPKM 0.8) and 20 other tissues See more
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    Genomic context

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    See LOC105376689 in Genome Data Viewer
    Location:
    1p36.23
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (7693124..7704562, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (7224174..7235612, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (7753184..7764622, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene calmodulin binding transcription activator 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7517439-7518106 Neighboring gene CAMTA1 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7530650-7531194 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7532917-7533608 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7551761-7552396 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7560506-7561006 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7561007-7561507 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7562099-7562599 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7563077-7563934 Neighboring gene uncharacterized LOC105376691 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7563935-7564790 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7565577-7566214 Neighboring gene MPRA-validated peak36 silencer Neighboring gene MPRA-validated peak35 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7594027-7595006 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7598278-7598983 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7643497-7643996 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7646449-7647169 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7655704-7656204 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7668502-7669038 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7669039-7669576 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7669577-7670113 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7670114-7670651 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7673507-7674037 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7672975-7673506 Neighboring gene MPRA-validated peak37 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7685250-7685750 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7695174-7696155 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7700515-7701015 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7702117-7703085 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7703871-7704371 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7710763-7711264 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7711265-7711764 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:7717029-7717568 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7723269-7723770 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 90 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:7729239-7730085 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 185 Neighboring gene MPRA-validated peak40 silencer Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:7798026-7799225 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:7830560-7831256 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:7831283-7831525 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 186 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 187 Neighboring gene uncharacterized LOC124903833 Neighboring gene MPRA-validated peak42 silencer Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:7886590-7887789 Neighboring gene vesicle associated membrane protein 3 Neighboring gene period circadian regulator 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_188652.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL359881

    2. NR_188653.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL359881

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      7693124..7704562 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      7224174..7235612 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials