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    MIR1915HG MIR1915 host gene [ Homo sapiens (human) ]

    Gene ID: 399726, updated on 17-Sep-2024

    Summary

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    Official Symbol
    MIR1915HGprovided by HGNC
    Official Full Name
    MIR1915 host geneprovided by HGNC
    Primary source
    HGNC:HGNC:31448
    See related
    Ensembl:ENSG00000204682 AllianceGenome:HGNC:31448
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CASC10; C10orf114; bA418C1.3
    Expression
    Broad expression in kidney (RPKM 3.7), liver (RPKM 3.6) and 15 other tissues See more
    Orthologs
    all
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    Genomic context

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    See MIR1915HG in Genome Data Viewer
    Location:
    10p12.31
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (21492658..21497260, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (21511792..21516394, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (21781587..21786189, complement)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376445 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:21706197-21706710 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:21760456-21760650 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr10:21761953-21762749 Neighboring gene uncharacterized LOC124902598 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21783452-21784245 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2186 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2187 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2188 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:21793394-21793626 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2189 Neighboring gene microRNA 1915 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21814003-21814646 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21814647-21815290 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2191 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2192 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:21816390-21816548 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr10:21817867-21818510 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21822730-21823443 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2196 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2197 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:21824159-21824871 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21825135-21825648 Neighboring gene SKI/DACH domain containing 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:21840002-21840186 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:21844418-21845000 Neighboring gene MLLT10 histone lysine methyltransferase DOT1L cofactor Neighboring gene RNA, U6 small nuclear 306, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Common variation at 10p12.31 near MLLT10 influences meningioma risk. Dobbins SE, et al. Nat Genet, 2011 Jul 31. PMID 21804547, Free PMC Article
    2. The DNA sequence and comparative analysis of human chromosome 10. Deloukas P, et al. Nature, 2004 May 27. PMID 15164054
    3. High-throughput analyses of hnRNP H1 dissects its multi-functional aspect. Uren PJ, et al. RNA Biol, 2016. PMID 26760575, Free PMC Article
    4. Ubiquitin-mediated proteolysis of HuR by heat shock. Abdelmohsen K, et al. EMBO J, 2009 May 6. PMID 19322201, Free PMC Article
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Other Names

    • cancer susceptibility 10
    • cancer susceptibility candidate 10
    • cancer susceptibility candidate gene 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_160800.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL358780
      Related
      ENST00000658000.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      21492658..21497260 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      21511792..21516394 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001010911.3: Suppressed sequence

      Description
      NM_001010911.3: This RefSeq was removed because it is now thought that this gene does not encode a protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5T4H9.1 GenPept UniProtKB/Swiss-Prot:Q5T4H9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
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