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    pqsL monooxygenase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 880329, updated on 24-Aug-2024

    Summary

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    Gene symbol
    pqsL
    Gene description
    monooxygenase
    Locus tag
    PA4190
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (4687652..4688848)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily transporter Neighboring gene hypothetical protein Neighboring gene aldehyde dehydrogenase Neighboring gene iron/ascorbate oxidoreductase Neighboring gene ABC transporter ATP-binding protein Neighboring gene ABC transporter permease

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer. Ernst S, et al. Nat Commun, 2020 May 25. PMID 32451409, Free PMC Article
    2. PqsL uses reduced flavin to produce 2-hydroxylaminobenzoylacetate, a preferred PqsBC substrate in alkyl quinolone biosynthesis in Pseudomonas aeruginosa. Drees SL, et al. J Biol Chem, 2018 Jun 15. PMID 29669807, Free PMC Article
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer.
      Title: Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer.
    2. This study completes the Alkyl hydroxyquinoline N-oxides biosynthetic pathway in P. aeruginosa, indicating that PqsL produces the unstable product 2-hydroxylaminobenzoylacetate from 2-ABA and depends on free reduced flavin as electron donor instead of NAD(P)H.
      Title: PqsL uses reduced flavin to produce 2-hydroxylaminobenzoylacetate, a preferred PqsBC substrate in alkyl quinolone biosynthesis in Pseudomonas aeruginosa.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    monooxygenase
    NP_252879.1
    • 'Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)'

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      4687652..4688848
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252879.1 monooxygenase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252879.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q9HWJ1
      Conserved Domains (1) summary
      PRK07045
      Location:1 → 388
      PRK07045; putative monooxygenase; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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