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    pilO type 4 fimbrial biogenesis protein PilO [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 880985, updated on 11-Sep-2024

    Summary

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    Gene symbol
    pilO
    Gene description
    type 4 fimbrial biogenesis protein PilO
    Locus tag
    PA5042
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (5678433..5679056, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene shikimate kinase Neighboring gene type 4 fimbrial biogenesis outer membrane protein PilQ Neighboring gene type 4 fimbrial biogenesis protein PilP Neighboring gene type 4 fimbrial biogenesis protein PilN Neighboring gene type 4 fimbrial biogenesis protein PilM Neighboring gene penicillin-binding protein 1A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Periplasmic domains of Pseudomonas aeruginosa PilN and PilO form a stable heterodimeric complex. Sampaleanu LM, et al. J Mol Biol, 2009 Nov 20. PMID 19857646
    2. PilMNOPQ from the Pseudomonas aeruginosa type IV pilus system form a transenvelope protein interaction network that interacts with PilA. Tammam S, et al. J Bacteriol, 2013 May. PMID 23457250, Free PMC Article
    3. PilM/N/O/P proteins form an inner membrane complex that affects the stability of the Pseudomonas aeruginosa type IV pilus secretin. Ayers M, et al. J Mol Biol, 2009 Nov 20. PMID 19857645
    4. Characterization of the PilN, PilO and PilP type IVa pilus subcomplex. Tammam S, et al. Mol Microbiol, 2011 Dec. PMID 22053789
    5. Characterization of a five-gene cluster required for the biogenesis of type 4 fimbriae in Pseudomonas aeruginosa. Martin PR, et al. Mol Microbiol, 1995 May. PMID 7565110

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PilP interacts with the N0 segment of PilQ via its C-terminal domain, and that the N-terminal cytoplasmic tail of PilN binds to the actin-like protein PilM, connecting all cellular compartments via the PilMNOPQ protein interaction network.
      Title: PilMNOPQ from the Pseudomonas aeruginosa type IV pilus system form a transenvelope protein interaction network that interacts with PilA.
    2. PilN, PilO and PilP interact directly to form a stable heterotrimeric complex.
      Title: Characterization of the PilN, PilO and PilP type IVa pilus subcomplex.
    3. PilN/O heterodimers form the foundation of the inner-membrane PilM/N/O/P complex, which is critical for the assembly of a functional type IV pili complex.
      Title: Periplasmic domains of Pseudomonas aeruginosa PilN and PilO form a stable heterodimeric complex.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within type IV pilus assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within type IV pilus-dependent motility IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in type IV pilus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    type 4 fimbrial biogenesis protein PilO
    NP_253729.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      5678433..5679056 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_253729.1 type 4 fimbrial biogenesis protein PilO [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_253729.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      G3XD51, Q51353
      Conserved Domains (1) summary
      COG3167
      Location:8 → 207
      PilO; Tfp pilus assembly protein PilO [Cell motility, Extracellular structures]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    G3XD51.1

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    Research Materials