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    MYG1 Myg1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856900, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MYG1
    Official Full Name
    Myg1p
    Primary source
    SGD:S000000958
    Locus tag
    YER156C
    See related
    AllianceGenome:SGD:S000000958; FungiDB:YER156C; VEuPathDB:YER156C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in positive regulation of cellular respiration. Located in chromatin and nucleus. Used to study vitiligo. Orthologous to human MYG1 (MYG1 exonuclease). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MYG1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (483325..484341, complement)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene membrane insertase OXA1 Neighboring gene GTPase-activating protein BEM2 Neighboring gene Golgi transport complex subunit COG3 Neighboring gene tRNA-Glu

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular interaction network of the Hsp90 chaperone system. Zhao R, et al. Adv Exp Med Biol, 2007. PMID 17205672
    2. Myg1 exonuclease couples the nuclear and mitochondrial translational programs through RNA processing. Grover R, et al. Nucleic Acids Res, 2019 Jun 20. PMID 31081026, Free PMC Article
    3. Gene expression profiling and phenotype analyses of S. cerevisiae in response to changing copper reveals six genes with new roles in copper and iron metabolism. van Bakel H, et al. Physiol Genomics, 2005 Aug 11. PMID 15886332
    4. Exploratory and confirmatory gene expression profiling of mac1Delta. De Freitas JM, et al. J Biol Chem, 2004 Feb 6. PMID 14534306
    5. The SUN protein Mps3 is required for spindle pole body insertion into the nuclear membrane and nuclear envelope homeostasis. Friederichs JM, et al. PLoS Genet, 2011 Nov. PMID 22125491, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of cellular respiration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Myg1p
    NP_011083.3
    • Protein involved in mitochondrial function; interacts with Hsp82p and copurifies with Ipl1p; expression is copper responsive and downregulated in strains deleted for MAC1, a copper-responsive transcription factor; role in preventing L-A mycovirus pathogenesis; human homolog MYG1 is linked to developmental processes and dermatological diseases, complements yeast null mutant

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      483325..484341 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179046.3 → NP_011083.3  TPA: Myg1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011083.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DM63, P40093
      UniProtKB/TrEMBL
      A6ZRB3, B3LRR9, C7GQ40, G2WD43
      Conserved Domains (1) summary
      pfam03690
      Location:16 → 337
      UPF0160; Uncharacterized protein family (UPF0160)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40093.1

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