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    COG7 Golgi transport complex subunit COG7 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852879, updated on 9-Dec-2024

    Summary

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    Official Symbol
    COG7
    Official Full Name
    Golgi transport complex subunit COG7
    Primary source
    SGD:S000002973
    Locus tag
    YGL005C
    See related
    AllianceGenome:SGD:S000002973; FungiDB:YGL005C; VEuPathDB:YGL005C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    COD5
    Summary
    Involved in cytoplasm to vacuole targeting by the Cvt pathway and intra-Golgi vesicle-mediated transport. Located in cytosol and mitochondrion. Part of Golgi transport complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See COG7 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (489708..490547, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene calcium-transporting ATPase PMC1 Neighboring gene Rpn14p Neighboring gene Cdh1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic interaction network has a very limited impact on the evolutionary trajectories in continuous culture-grown populations of yeast. Klim J, et al. BMC Ecol Evol, 2021 May 26. PMID 34039270, Free PMC Article
    2. Cog5-Cog7 crystal structure reveals interactions essential for the function of a multisubunit tethering complex. Ha JY, et al. Proc Natl Acad Sci U S A, 2014 Nov 4. PMID 25331899, Free PMC Article
    3. Molecular architecture of the complete COG tethering complex. Ha JY, et al. Nat Struct Mol Biol, 2016 Aug. PMID 27428773, Free PMC Article
    4. Detailed Analysis of the Interaction of Yeast COG Complex. Ishii M, et al. Cell Struct Funct, 2018 Jul 19. PMID 29899178, Free PMC Article
    5. Cog1p plays a central role in the organization of the yeast conserved oligomeric Golgi complex. Fotso P, et al. J Biol Chem, 2005 Jul 29. PMID 15932880

    See all (63) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasm to vacuole targeting by the Cvt pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in intra-Golgi vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of Golgi transport complex IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    Golgi transport complex subunit COG7
    NP_011510.1
    • Component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      489708..490547 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180870.1 → NP_011510.1  TPA: Golgi transport complex subunit COG7 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011510.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VUD3, E9P921, P53195
      UniProtKB/TrEMBL
      G2WE89, N1P3D3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53195.1

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