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    YHI9 Yhi9p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856424, updated on 9-Dec-2024

    Summary

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    Official Symbol
    YHI9
    Official Full Name
    Yhi9p
    Primary source
    SGD:S000001071
    Locus tag
    YHR029C
    See related
    AllianceGenome:SGD:S000001071; FungiDB:YHR029C; VEuPathDB:YHR029C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable isomerase activity. Involved in endoplasmic reticulum unfolded protein response. Located in chromatin. Orthologous to human PBLD (phenazine biosynthesis like protein domain containing). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See YHI9 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (167677..168561, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene proteasome regulatory particle base subunit RPN1 Neighboring gene dipeptidyl aminopeptidase Neighboring gene mitogen-activated serine/threonine-protein kinase SLT2 Neighboring gene DNA helicase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily. Liger D, et al. Proteins, 2005 Sep 1. PMID 16021630
    2. Genomic analysis of the Opi- phenotype. Hancock LC, et al. Genetics, 2006 Jun. PMID 16582425, Free PMC Article
    3. Discovery and identification of genes involved in DNA damage repair in yeast. Jagadeesan SK, et al. Gene, 2022 Jul 15. PMID 35569766
    4. APEX2-mediated proximity labeling resolves protein networks in Saccharomyces cerevisiae cells. Singer-Krüger B, et al. FEBS J, 2020 Jan. PMID 31323700
    5. Analysis of the vacuolar luminal proteome of Saccharomyces cerevisiae. Sarry JE, et al. FEBS J, 2007 Aug. PMID 17651441

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. YHI9 has a fold similar to bacterial diaminopimelate epimerase, revealing a bimodular structure with an internal symmetry
      Title: Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in endoplasmic reticulum unfolded protein response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Yhi9p
    NP_011894.1
    • hypothetical protein; null mutant is defective in unfolded protein response; possibly involved in a membrane regulation metabolic pathway; member of the PhzF superfamily, though most likely not involved in phenazine production

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      167677..168561 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179159.1 → NP_011894.1  TPA: Yhi9p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011894.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DKX6, P38765
      UniProtKB/TrEMBL
      A6ZST5, B3LSF0, B5VJW0, C7GTV1, C8ZA97, N1P1J3
      Conserved Domains (1) summary
      TIGR00654
      Location:3 → 294
      PhzF_family; phenazine biosynthesis protein PhzF family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38765.1

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