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    ESL1 Esl1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854655, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ESL1
    Official Full Name
    Esl1p
    Primary source
    SGD:S000001413
    Locus tag
    YIL151C
    See related
    AllianceGenome:SGD:S000001413; FungiDB:YIL151C; VEuPathDB:YIL151C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable telomerase RNA binding activity and telomeric DNA binding activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to be part of telomerase holoenzyme complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ESL1 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (57338..60694, complement)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase RRD1 Neighboring gene Vpr1p Neighboring gene Mcm10p Neighboring gene Mlp2p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic suppressors of Δgrx3 Δgrx4, lacking redundant multidomain monothiol yeast glutaredoxins, rescue growth and iron homeostasis. Li G, et al. Biosci Rep, 2022 Jun 30. PMID 35593209, Free PMC Article
    2. The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. Bleichert F, et al. Proc Natl Acad Sci U S A, 2006 Jun 20. PMID 16769905, Free PMC Article
    3. Yeast hEST1A/B (SMG5/6)-like proteins contribute to environment-sensing adaptive gene expression responses. Lai X, et al. G3 (Bethesda), 2013 Oct 3. PMID 23893744, Free PMC Article
    4. The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes. Schäfer T, et al. EMBO J, 2003 Mar 17. PMID 12628929, Free PMC Article
    5. Interaction of CK1δ with γTuSC ensures proper microtubule assembly and spindle positioning. Peng Y, et al. Mol Biol Cell, 2015 Jul 1. PMID 25971801, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables telomerase RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables telomeric DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    part_of telomerase holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Esl1p
    NP_012115.1
    • hEST1A/B (SMG5/6)-like protein; contributes to environment-sensing adaptive gene expression responses; Esl1p and Esl2p contain a 14-3-3-like domain and a putative PilT N-terminus ribonuclease domain; ESL1 has a paralog, ESL2, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      57338..60694 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179499.1 → NP_012115.1  TPA: Esl1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012115.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVD6, P40456
      UniProtKB/TrEMBL
      A6ZVC5, B5VKG0, C7GUR7, N1P494
      Conserved Domains (1) summary
      cl28905
      Location:949 → 1090
      PIN_SF; PIN (PilT N terminus) domain: Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40456.1

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