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    TMH18 Tmh18p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856213, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TMH18
    Official Full Name
    Tmh18p
    Primary source
    SGD:S000006302
    Locus tag
    YPR098C
    See related
    AllianceGenome:SGD:S000006302; FungiDB:YPR098C; VEuPathDB:YPR098C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in mitochondrial outer membrane. Orthologous to human TMEM205 (transmembrane protein 205). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See TMH18 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    2
    Sequence:
    Chromosome: XVI; NC_001148.4 (728947..729528, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Lec1p Neighboring gene uncharacterized protein Neighboring gene mitochondrial 54S ribosomal protein MRPL51 Neighboring gene Snt309p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale. Morgenstern M, et al. Cell Rep, 2017 Jun 27. PMID 28658629, Free PMC Article
    2. Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Zahedi RP, et al. Mol Biol Cell, 2006 Mar. PMID 16407407, Free PMC Article
    3. MitoStores: chaperone-controlled protein granules store mitochondrial precursors in the cytosol. Krämer L, et al. EMBO J, 2023 Apr 3. PMID 36704946, Free PMC Article
    4. INA complex liaises the F(1)F(o)-ATP synthase membrane motor modules. Naumenko N, et al. Nat Commun, 2017 Nov 1. PMID 29093463, Free PMC Article
    5. Recruitment of Cytosolic J-Proteins by TOM Receptors Promotes Mitochondrial Protein Biogenesis. Opaliński Ł, et al. Cell Rep, 2018 Nov 20. PMID 30463002, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial outer membrane HDA PubMed 
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Tmh18p
    NP_015423.2
    • Mitochondrial hypothetical protein; localized to the mitochondrial outer membrane

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      728947..729528 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184195.1 → NP_015423.2  TPA: Tmh18p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015423.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W497, Q06089
      UniProtKB/TrEMBL
      A6ZWX9, B3LK63, C8ZJC0, G2WPR5, N1NWF1
      Conserved Domains (1) summary
      pfam13664
      Location:11 → 105
      DUF4149; Domain of unknown function (DUF4149)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06089.2

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