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    pscF type III export protein PscF [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 879634, updated on 24-Aug-2024

    Summary

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    Gene symbol
    pscF
    Gene description
    type III export protein PscF
    Locus tag
    PA1719
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (1862764..1863021)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene type III export apparatus protein Neighboring gene type III secretion outer membrane protein PscC Neighboring gene type III export protein PscD Neighboring gene type III export protein PscE Neighboring gene type III export protein PscG Neighboring gene type III export protein PscH Neighboring gene type III export protein PscI Neighboring gene type III export protein PscJ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Structure-Function-Inhibition Analysis of the Pseudomonas aeruginosa Type III Secretion Needle Protein PscF. Moir DT, et al. J Bacteriol, 2020 Aug 25. PMID 32601072, Free PMC Article
    2. PscF is a major component of the Pseudomonas aeruginosa type III secretion needle. Pastor A, et al. FEMS Microbiol Lett, 2005 Dec 1. PMID 16239085
    3. Exoenzyme S of Pseudomonas aeruginosa is secreted by a type III pathway. Yahr TL, et al. Mol Microbiol, 1996 Dec. PMID 8971719
    4. The PscE-PscF-PscG complex controls type III secretion needle biogenesis in Pseudomonas aeruginosa. Quinaud M, et al. J Biol Chem, 2005 Oct 28. PMID 16115870
    5. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A Structure-Function-Inhibition Analysis of the Pseudomonas aeruginosa Type III Secretion Needle Protein PscF.
      Title: A Structure-Function-Inhibition Analysis of the Pseudomonas aeruginosa Type III Secretion Needle Protein PscF.
    2. PscE and PscG prevent PscF from polymerizing prematurely in the P. aeruginosa cytoplasm and keep it in a secretion prone conformation
      Title: The PscE-PscF-PscG complex controls type III secretion needle biogenesis in Pseudomonas aeruginosa.
    3. the P. aeruginosa type III secretory needle structure is composed essentially of PscF, a protein required for secretion and P. aeruginosa cytotoxicity
      Title: PscF is a major component of the Pseudomonas aeruginosa type III secretion needle.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within protein secretion by the type III secretion system IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within protein secretion by the type III secretion system IGC
    Inferred from Genomic Context
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of type III protein secretion system complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    type III export protein PscF
    NP_250410.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      1862764..1863021
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_250410.1 type III export protein PscF [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_250410.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P95434
      Conserved Domains (1) summary
      pfam09392
      Location:16 → 84
      T3SS_needle_F; Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P95434.3

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