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    narH respiratory nitrate reductase subunit beta [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 879783, updated on 24-Aug-2024

    Summary

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    Gene symbol
    narH
    Gene description
    respiratory nitrate reductase subunit beta
    Locus tag
    PA3874
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (4336708..4338249, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene respiratory nitrate reductase subunit gamma Neighboring gene respiratory nitrate reductase subunit delta Neighboring gene respiratory nitrate reductase subunit alpha Neighboring gene nitrite extrusion protein 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fosfomycin and tobramycin in combination downregulate nitrate reductase genes narG and narH, resulting in increased activity against Pseudomonas aeruginosa under anaerobic conditions. McCaughey G, et al. Antimicrob Agents Chemother, 2013 Nov. PMID 23959314, Free PMC Article
    2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
    5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Down-regulation of narG and narH expression increases the susceptibility of Pseudomonas aeruginosa towards antibiotics.
      Title: Fosfomycin and tobramycin in combination downregulate nitrate reductase genes narG and narH, resulting in increased activity against Pseudomonas aeruginosa under anaerobic conditions.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    respiratory nitrate reductase subunit beta
    NP_252563.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      4336708..4338249 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_252563.1 respiratory nitrate reductase subunit beta [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_252563.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      G3XD87, O54044
      Conserved Domains (1) summary
      COG1140
      Location:1 → 513
      NarY; Nitrate reductase beta subunit [Energy production and conversion, Inorganic ion transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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