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    pyridoxal 5'-phosphate synthase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851178, updated on 9-Dec-2024

    Summary

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    Official Full Name
    pyridoxal 5'-phosphate synthase
    Primary source
    SGD:S000004448
    Locus tag
    YLR456W
    See related
    AllianceGenome:SGD:S000004448; FungiDB:YLR456W; VEuPathDB:YLR456W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (1055070..1055684)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene tRNA-Ile Neighboring gene Pdp3p Neighboring gene Nbp1p Neighboring gene GPI-anchor transamidase subunit GAB1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomewide screening for genes associated with gliotoxin resistance and sensitivity in Saccharomyces cerevisiae. Chamilos G, et al. Antimicrob Agents Chemother, 2008 Apr. PMID 18212113, Free PMC Article
    2. Oxidant-induced cell-cycle delay in Saccharomyces cerevisiae: the involvement of the SWI6 transcription factor. Fong CS, et al. FEMS Yeast Res, 2008 May. PMID 18205808
    3. Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens. Fromont-Racine M, et al. Nat Genet, 1997 Jul. PMID 9207794
    4. Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis. Vizeacoumar FJ, et al. J Cell Biol, 2010 Jan 11. PMID 20065090, Free PMC Article
    5. The nucleotide sequence of Saccharomyces cerevisiae chromosome XII. Johnston M, et al. Nature, 1997 May 29. PMID 9169871, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. does not function as a pyridoxamine 5'-phosphate oxidase
      Title: Experimental Evidence for a Revision in the Annotation of Putative Pyridoxamine 5'-Phosphate Oxidases P(N/M)P from Fungi.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    pyridoxal 5'-phosphate synthase
    NP_013561.1
    • hypothetical protein; predicted to encode a pyridoxal 5'-phosphate synthase based on sequence similarity but purified protein does not possess this activity, nor does it bind flavin mononucleotide (FMN); null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2; YLR456W has a paralog, YPR172W, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      1055070..1055684
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182344.1 → NP_013561.1  TPA: pyridoxal 5'-phosphate synthase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013561.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZ90, Q06199
      UniProtKB/TrEMBL
      A7A1X7, G2WJR7, N1NYX2
      Conserved Domains (1) summary
      pfam01243
      Location:7 → 90
      Putative_PNPOx; Pyridoxamine 5'-phosphate oxidase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06199.1

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