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    PPP1R14B-AS1 PPP1R14B antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 105369340, updated on 10-Dec-2024

    Summary

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    Official Symbol
    PPP1R14B-AS1provided by HGNC
    Official Full Name
    PPP1R14B antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:54233
    See related
    Ensembl:ENSG00000256940 AllianceGenome:HGNC:54233
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Broad expression in testis (RPKM 7.9), duodenum (RPKM 3.8) and 18 other tissues See more
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    Genomic context

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    See PPP1R14B-AS1 in Genome Data Viewer
    Location:
    11q13.1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (64245866..64248214)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (64235887..64238235)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (64013338..64015686)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3466 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3467 Neighboring gene vascular endothelial growth factor B Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:64007574-64008476 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:64008477-64009377 Neighboring gene uncharacterized LOC114841035 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3469 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:64010280-64011180 Neighboring gene FKBP prolyl isomerase 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3470 Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 14B Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3471 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:64015853-64016500 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:64016501-64017146 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:64017147-64017794 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:64019089-64019734 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:64019735-64020381 Neighboring gene phospholipase C beta 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4892 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4893 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3473 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4894 Neighboring gene H3K27ac hESC enhancer GRCh37_chr11:64038093-64038658 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4895 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4896 Neighboring gene G protein-coupled receptor 137 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:64042574-64043234 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:64043895-64044554 Neighboring gene BCL2 associated agonist of cell death Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:64046081-64046582 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3474

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Long noncoding RNA PPP1R14B-AS1 imitates microRNA-134-3p to facilitate breast cancer progression by upregulating LIM and SH3 protein 1. Zhou L, et al. Oncol Res, 2021. PMID 37303940, Free PMC Article
    2. Creation of genome-wide protein expression libraries using random activation of gene expression. Harrington JJ, et al. Nat Biotechnol, 2001 May. PMID 11329013

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Long noncoding RNA PPP1R14B-AS1 imitates microRNA-134-3p to facilitate breast cancer progression by upregulating LIM and SH3 protein 1.
      Title: Long noncoding RNA PPP1R14B-AS1 imitates microRNA-134-3p to facilitate breast cancer progression by upregulating LIM and SH3 protein 1.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_135086.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate 5' exon resulting in a shorter transcript compared to variant 1.
      Source sequence(s)
      AI383738, BG206029, BU568128
      Related
      ENST00000538355.1

    2. NR_135087.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AP001453, BG206029, BI518361
      Related
      ENST00000544553.4

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      64245866..64248214
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      64235887..64238235
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials