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    trpp-10 Trafficking protein particle complex subunit 10 [ Caenorhabditis elegans ]

    Gene ID: 3564796, updated on 9-Dec-2024

    Summary

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    Official Symbol
    trpp-10
    Official Full Name
    Trafficking protein particle complex subunit 10
    Primary source
    WormBase:WBGene00022138
    Locus tag
    CELE_Y71G12A.2
    See related
    AllianceGenome:WB:WBGene00022138
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in early endosome to Golgi transport and intra-Golgi vesicle-mediated transport. Predicted to be located in cytosol. Predicted to be part of TRAPPII protein complex. Orthologous to human TRAPPC10 (trafficking protein particle complex subunit 10). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See trpp-10 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    16
    Sequence:
    Chromosome: I; NC_003279.8 (1895161..1923240)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Tubby C-terminal domain-containing protein Neighboring gene AB hydrolase-1 domain-containing protein Neighboring gene MD-2-related lipid-recognition domain-containing protein Neighboring gene ncRNA Neighboring gene beta-N-acetylhexosaminidase Neighboring gene Aa_trans domain-containing protein;Amino acid transporter transmembrane domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. N-glycan antennal modifications are altered in Caenorhabditis elegans lacking the HEX-4 N-acetylgalactosamine-specific hexosaminidase. Paschinger K, et al. J Biol Chem, 2023 Apr. PMID 36813232, Free PMC Article
    2. The relationship between intraflagellar transport and upstream protein trafficking pathways and macrocyclic lactone resistance in Caenorhabditis elegans. Brinzer RA, et al. G3 (Bethesda), 2024 Mar 6. PMID 38227795, Free PMC Article
    3. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in Golgi vesicle transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in early endosome to Golgi transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of TRAPPII protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of TRAPPII protein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Trafficking protein particle complex subunit 10
    NP_001122554.2
    • Confirmed by transcript evidence
    NP_001364798.1
    • Confirmed by transcript evidence
    NP_001380102.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      1895161..1923240
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001377686.1 → NP_001364798.1  Trafficking protein particle complex subunit 10 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9BL51

    2. NM_001129082.4 → NP_001122554.2  Trafficking protein particle complex subunit 10 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122554.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B1V899
      Conserved Domains (1) summary
      pfam12584
      Location:959 → 1081
      TRAPPC10; Trafficking protein particle complex subunit 10, TRAPPC10

    3. NM_001392996.1 → NP_001380102.1  Trafficking protein particle complex subunit 10 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0P2
      Conserved Domains (1) summary
      pfam12584
      Location:126 → 248
      TRAPPC10; Trafficking protein particle complex subunit 10, TRAPPC10
    Nucleotide Protein
    Heading Accession and Version

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