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    rbc-2 WD_REPEATS_REGION domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 190267, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rbc-2
    Official Full Name
    WD_REPEATS_REGION domain-containing protein
    Primary source
    WormBase:WBGene00004314
    Locus tag
    CELE_Y54F10AM.10
    See related
    AllianceGenome:WB:WBGene00004314
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in cytoplasm. Orthologous to human WDR7 (WD repeat domain 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rbc-2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    18
    Sequence:
    Chromosome: III; NC_003281.10 (2511648..2528689, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene GDT1 family protein Neighboring gene Putative phospholipase B-like 3 Neighboring gene Secreted protein Neighboring gene Uncharacterized protein Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 Neighboring gene Homeobox protein cut-like ceh-44 Neighboring gene Protein CASP

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    WD_REPEATS_REGION domain-containing protein
    NP_001368042.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      2511648..2528689 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381780.3 → NP_001368042.1  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9BL05
      Conserved Domains (2) summary
      sd00039
      Location:33 → 68
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:373 → 621
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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