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    wbp-4 U1-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173027, updated on 9-Dec-2024

    Summary

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    Official Symbol
    wbp-4
    Official Full Name
    U1-type domain-containing protein
    Primary source
    WormBase:WBGene00010159
    Locus tag
    CELE_F56G4.4
    See related
    AllianceGenome:WB:WBGene00010159
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in RNA splicing. Predicted to be part of precatalytic spliceosome. Orthologous to human WBP4 (WW domain binding protein 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See wbp-4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (11374620..11380127)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene F-box associated domain-containing protein Neighboring gene Rod_C domain-containing protein Neighboring gene Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Neighboring gene ncRNA Neighboring gene Amino acid transporter Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multiple phenotypes resulting from a mutagenesis screen for pharynx muscle mutations in Caenorhabditis elegans. Ferrier A, et al. PLoS One, 2011. PMID 22073173, Free PMC Article
    2. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    3. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    U1-type domain-containing protein
    NP_492912.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      11374620..11380127
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060511.5 → NP_492912.1  U1-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492912.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XUY1
      Conserved Domains (1) summary
      smart00451
      Location:8 → 43
      ZnF_U1; U1-like zinc finger
    Nucleotide Protein
    Heading Accession and Version

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