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    cec-10 Chromo domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172038, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cec-10
    Official Full Name
    Chromo domain-containing protein
    Primary source
    WormBase:WBGene00022831
    Locus tag
    CELE_ZK973.2
    See related
    AllianceGenome:WB:WBGene00022831
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of MBF transcription complex and SBF transcription complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cec-10 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    9
    Sequence:
    Chromosome: I; NC_003279.8 (4373656..4379321)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene PPM-type phosphatase domain-containing protein Neighboring gene SS18 N-terminal domain-containing protein Neighboring gene NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial Neighboring gene Thioredoxin domain-containing protein Neighboring gene S1 motif domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of MBF transcription complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase II transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of SBF transcription complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Chromo domain-containing protein
    NP_491360.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4373656..4379321
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058959.9 → NP_491360.1  Chromo domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491360.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N4L7
      Conserved Domains (3) summary
      cd00024
      Location:49 → 101
      CHROMO; Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence ...
      cd00204
      Location:517 → 577
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam13637
      Location:522 → 574
      Ank_4; Ankyrin repeats (many copies)
    Nucleotide Protein
    Heading Accession and Version

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