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    rips-1 Methyltransferase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178795, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rips-1
    Official Full Name
    Methyltransferase domain-containing protein
    Primary source
    WormBase:WBGene00019963
    Locus tag
    CELE_R08E5.3
    See related
    AllianceGenome:WB:WBGene00019963
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Is expressed in hypodermis and intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rips-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (3772021..3774609)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Dauer Up-Regulated Neighboring gene Dauer Up-Regulated Neighboring gene Methyltransferase domain-containing protein Neighboring gene Cysteine synthase 3 Neighboring gene Glycosyl-hydrolase family 116 catalytic region domain-containing protein;Non-lysosomal glucosylceramidase Neighboring gene Peroxidase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dithiothreitol causes toxicity in C. elegans by modulating the methionine-homocysteine cycle. G G, et al. Elife, 2022 Apr 19. PMID 35438636, Free PMC Article
    2. Thiol reductive stress activates the hypoxia response pathway. Ravi, et al. EMBO J, 2023 Nov 15. PMID 37902464, Free PMC Article
    3. Dietary-derived vitamin B12 protects Caenorhabditis elegans from thiol-reducing agents. Winter AD, et al. BMC Biol, 2022 Oct 8. PMID 36209095, Free PMC Article
    4. Genome-wide analysis of sex-enriched gene expression during C. elegans larval development. Thoemke K, et al. Dev Biol, 2005 Aug 15. PMID 15987632
    5. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Methyltransferase domain-containing protein
    NP_504045.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      3772021..3774609
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071644.8 → NP_504045.1  Methyltransferase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504045.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01593
      Conserved Domains (1) summary
      pfam13847
      Location:175 → 283
      Methyltransf_31; Methyltransferase domain
    Nucleotide Protein
    Heading Accession and Version

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