Y39B6A.33 Ribosome biogenesis protein NOP53 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: Y39B6A.33
Official Full Name: Ribosome biogenesis protein NOP53
Primary source: WormBase:WBGene00012692
Locus tag: CELE_Y39B6A.33
See related: AllianceGenome:WB:WBGene00012692
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable 5S rRNA binding activity. Involved in positive regulation of cellular respiration. Located in nucleolus. Orthologous to human NOP53 (NOP53 ribosome biogenesis factor). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See Y39B6A.33 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 4

Sequence:: Chromosome: V; NC_003283.11 (19001956..19006722)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y39B6B.o (e-PCR)
- UniSTS:324073

Y39B6B.p (e-PCR)
- UniSTS:324600

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables 5S rRNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in positive regulation of cellular respiration	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in rRNA processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosomal large subunit assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosomal large subunit assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in ribosome biogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleolus	HDA more info	PubMed
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Ribosome biogenesis protein NOP53

NP_001367001.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

19001956..19006722

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001380869.2 → NP_001367001.1 Ribosome biogenesis protein NOP53 [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9NEU5

Conserved Domains (1) summary

pfam07767
Location:15 → 397

Nop53; Nop53 (60S ribosomal biogenesis)