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    C48E7.6 Chondroitin sulfate proteoglycan 4 [ Caenorhabditis elegans ]

    Gene ID: 172317, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C48E7.6
    Official Full Name
    Chondroitin sulfate proteoglycan 4
    Primary source
    WormBase:WBGene00016751
    Locus tag
    CELE_C48E7.6
    See related
    AllianceGenome:WB:WBGene00016751
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in anatomical structure morphogenesis. Predicted to be located in membrane. Predicted to be active in collagen-containing extracellular matrix. Human ortholog(s) of this gene implicated in relapsing-remitting multiple sclerosis. Orthologous to human CSPG4 (chondroitin sulfate proteoglycan 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C48E7.6 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    30
    Sequence:
    Chromosome: I; NC_003279.8 (6236134..6249860)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Col_cuticle_N domain-containing protein Neighboring gene MS Related Protein Neighboring gene ncRNA Neighboring gene Saposin B-type domain-containing protein Neighboring gene Olfactomedin-like domain-containing protein Neighboring gene CCAAT/enhancer-binding protein homolog 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in anatomical structure morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in collagen-containing extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Chondroitin sulfate proteoglycan 4
    NP_001361945.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      6236134..6249860
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001374899.2 → NP_001361945.1  Chondroitin sulfate proteoglycan 4 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IG72
      Conserved Domains (1) summary
      pfam16184
      Location:1143 → 1247
      Cadherin_3; Cadherin-like
    Nucleotide Protein
    Heading Accession and Version

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