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    sra-12 Serpentine receptor class alpha-12 [ Caenorhabditis elegans ]

    Gene ID: 3565216, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sra-12
    Official Full Name
    Serpentine receptor class alpha-12
    Primary source
    WormBase:WBGene00005038
    Locus tag
    CELE_F44F4.7
    See related
    AllianceGenome:WB:WBGene00005038
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Is expressed in ASJL; ASJR; ASKL; and ASKR. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sra-12 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (10902756..10904479, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene SSD domain-containing protein Neighboring gene Serpentine receptor class alpha-10 Neighboring gene Core-2/I-Branching enzyme Neighboring gene Serpentine receptor class alpha-11 Neighboring gene Ovule protein;Transmembrane protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Complementary expression patterns of six nonessential Caenorhabditis elegans core 2/I N-acetylglucosaminyltransferase homologues. Warren CE, et al. Glycobiology, 2001 Nov. PMID 11744632
    2. The C. elegans G-protein-coupled receptor SRA-13 inhibits RAS/MAPK signalling during olfaction and vulval development. Battu G, et al. Development, 2003 Jun. PMID 12736202
    3. Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans. Troemel ER, et al. Cell, 1995 Oct 20. PMID 7585938
    4. Identification of a nematode chemosensory gene family. Chen N, et al. Proc Natl Acad Sci U S A, 2005 Jan 4. PMID 15618405, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sensory perception of chemical stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Serpentine receptor class alpha-12
    NP_496346.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      10902756..10904479 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063945.6 → NP_496346.2  Serpentine receptor class alpha-12 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496346.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q20410, Q962C7
      Conserved Domains (1) summary
      pfam02117
      Location:3 → 326
      7TM_GPCR_Sra; Serpentine type 7TM GPCR chemoreceptor Sra
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q20410.2

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