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    nhr-105 Nuclear Hormone Receptor family [ Caenorhabditis elegans ]

    Gene ID: 177476, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nhr-105
    Official Full Name
    Nuclear Hormone Receptor family
    Primary source
    WormBase:WBGene00003695
    Locus tag
    CELE_C06G3.1
    See related
    AllianceGenome:WB:WBGene00003695
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in head neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See nhr-105 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    10
    Sequence:
    Chromosome: IV; NC_003282.8 (7050156..7053450)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Mitochondrial import inner membrane translocase subunit Tim9 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Coordinate regulation of lipid metabolism by novel nuclear receptor partnerships. Pathare PP, et al. PLoS Genet, 2012. PMID 22511885, Free PMC Article
    2. Changes in Nuclear Receptor and Vitellogenin Gene Expression in Response to Steroids and Heavy Metal in Caenorhabditis elegans. Novillo A, et al. Integr Comp Biol, 2005 Jan. PMID 21676746
    3. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    4. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nuclear Hormone Receptor family
    NP_001021303.1
    • Product from WormBase gene class nhr;
      Confirmed by transcript evidence
    NP_001021304.1
    • Product from WormBase gene class nhr;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7050156..7053450
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001026132.7 → NP_001021303.1  Nuclear Hormone Receptor family [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021303.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17755, Q86PJ4
      Conserved Domains (2) summary
      cd06157
      Location:202 → 395
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
      smart00399
      Location:38 → 109
      ZnF_C4; c4 zinc finger in nuclear hormone receptors

    2. NM_001026133.7 → NP_001021304.1  Nuclear Hormone Receptor family [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021304.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q3LQX0
      Conserved Domains (2) summary
      cd06157
      Location:186 → 379
      NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
      smart00399
      Location:38 → 109
      ZnF_C4; c4 zinc finger in nuclear hormone receptors
    Nucleotide Protein
    Heading Accession and Version

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