Y44A6D.5 Branched-chain-amino-acid aminotransferase [Caenorhabditis elegans] - Gene

Summary

Official Symbol: Y44A6D.5
Official Full Name: Branched-chain-amino-acid aminotransferase
Primary source: WormBase:WBGene00012855
Locus tag: CELE_Y44A6D.5
See related: AllianceGenome:WB:WBGene00012855
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable branched-chain-amino-acid transaminase activity. Predicted to be involved in L-leucine biosynthetic process and L-valine biosynthetic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in hypervalinemia and hyperleucine-isoleucinemia. Orthologous to human BCAT2 (branched chain amino acid transaminase 2). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

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Function	Evidence Code	Pubs
enables L-isoleucine-2-oxoglutarate transaminase activity	IEA Inferred from Electronic Annotation more info
enables L-leucine-2-oxoglutarate transaminase activity	IEA Inferred from Electronic Annotation more info
enables L-valine-2-oxoglutarate transaminase activity	IEA Inferred from Electronic Annotation more info
enables branched-chain-amino-acid transaminase activity	IBA Inferred from Biological aspect of Ancestor more info
enables branched-chain-amino-acid transaminase activity	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables transaminase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in L-leucine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in L-valine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in amino acid biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in branched-chain amino acid biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in branched-chain amino acid metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

NP_508014.1

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The following sections contain reference sequences that belong to a specific genome build. Explain