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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001285833.1 → NP_001272762.1 NADPH oxidase 4 isoform 2
See identical proteins and their annotated locations for NP_001272762.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) uses an alternate splice junction at the 5' end of an exon and contains two additional alternate coding exons compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus and an alternate internal segment compared to isoform 1.
- Source sequence(s)
-
AC141329, AK149398, AK149455, BY001994, CJ227847
- Conserved Domains (2) summary
-
- cd06186
Location:237 → 542
- NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
- pfam01794
Location:17 → 130
- Ferric_reduct; Ferric reductase like transmembrane component
-
NM_001285835.1 → NP_001272764.1 NADPH oxidase 4 isoform 3
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) uses an alternate splice junction at the 5' end of an exon compared to variant 1. This difference causes translation initiation at a downstream AUG and results in an isoform (3) with a shorter N-terminus compared to isoform 1.
- Source sequence(s)
-
AK149398, AK149455, BY001994, CJ227847
- Conserved Domains (2) summary
-
- cd06186
Location:237 → 503
- NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
- pfam01794
Location:17 → 130
- Ferric_reduct; Ferric reductase like transmembrane component
-
NM_015760.5 → NP_056575.1 NADPH oxidase 4 isoform 1
See identical proteins and their annotated locations for NP_056575.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AK050371, AK149398, AK149455, BY001994, CJ227847
- Consensus CDS
-
CCDS21437.1
- UniProtKB/Swiss-Prot
- Q3TF39, Q8C3M1, Q8VCA3, Q9JHI8
- UniProtKB/TrEMBL
-
B2RSM1
- Related
- ENSMUSP00000032781.8, ENSMUST00000032781.14
- Conserved Domains (2) summary
-
- cd06186
Location:311 → 577
- NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
- pfam01794
Location:69 → 204
- Ferric_reduct; Ferric reductase like transmembrane component
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000073.7 Reference GRCm39 C57BL/6J
- Range
-
86893638..87047918
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_006508012.2 → XP_006508075.1 NADPH oxidase 4 isoform X4
- UniProtKB/Swiss-Prot
-
Q9JHI8
- Conserved Domains (2) summary
-
- cd06186
Location:311 → 616
- NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
- pfam01794
Location:69 → 204
- Ferric_reduct; Ferric reductase like transmembrane component
-
XM_017322347.2 → XP_017177836.1 NADPH oxidase 4 isoform X1
- Conserved Domains (2) summary
-
- cd06186
Location:311 → 576
- NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
- pfam01794
Location:69 → 204
- Ferric_reduct; Ferric reductase like transmembrane component
-
XM_006508011.4 → XP_006508074.1 NADPH oxidase 4 isoform X3
- Conserved Domains (2) summary
-
- pfam01794
Location:69 → 204
- Ferric_reduct; Ferric reductase like transmembrane component
- cl06868
Location:307 → 357
- FNR_like; Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport ...
-
XM_006508010.4 → XP_006508073.1 NADPH oxidase 4 isoform X2
- Conserved Domains (2) summary
-
- cd06186
Location:294 → 560
- NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
- pfam01794
Location:52 → 187
- Ferric_reduct; Ferric reductase like transmembrane component
RNA
-
XR_004934139.1 RNA Sequence