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    Gxylt1 glucoside xylosyltransferase 1 [ Mus musculus (house mouse) ]

    Gene ID: 223827, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Gxylt1provided by MGI
    Official Full Name
    glucoside xylosyltransferase 1provided by MGI
    Primary source
    MGI:MGI:2684933
    See related
    Ensembl:ENSMUSG00000036197 AllianceGenome:MGI:2684933
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm87; Glt8d3; Gm1228
    Summary
    Predicted to enable UDP-xylosyltransferase activity. Predicted to be involved in O-glycan processing. Predicted to be located in membrane. Orthologous to human GXYLT1 (glucoside xylosyltransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 6.5), placenta adult (RPKM 5.6) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Gxylt1 in Genome Data Viewer
    Location:
    15 E3; 15 47.34 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (93137611..93173060, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (93239730..93275336, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene tetratricopeptide repeat domain 5 pseudogene Neighboring gene STARR-seq mESC enhancer starr_39521 Neighboring gene predicted gene, 38535 Neighboring gene STARR-seq mESC enhancer starr_39522 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E945 Neighboring gene YY1 associated factor 2 Neighboring gene predicted gene, 52193 Neighboring gene predicted gene, 26371

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables UDP-xylosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-xylosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables UDP-xylosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in O-glycan processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in O-glycan processing ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in O-glycan processing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glucoside xylosyltransferase 1
    Names
    glycosyltransferase 8 domain containing 3
    glycosyltransferase 8 domain-containing protein 3
    NP_001028447.1
    NP_001333714.1
    NP_001343935.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033275.5 → NP_001028447.1  glucoside xylosyltransferase 1 isoform 1

      See identical proteins and their annotated locations for NP_001028447.1

      Status: VALIDATED

      Source sequence(s)
      AC127360
      Consensus CDS
      CCDS27764.1
      UniProtKB/Swiss-Prot
      Q3UHH8
      Related
      ENSMUSP00000047281.7, ENSMUST00000049484.13
      Conserved Domains (2) summary
      cd06430
      Location:80 → 352
      GT8_like_2; GT8_like_2 represents a subfamily of GT8 with unknown function
      COG1442
      Location:164 → 309
      RfaJ; Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis]

    2. NM_001346785.1 → NP_001333714.1  glucoside xylosyltransferase 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC127360
      Consensus CDS
      CCDS84189.1
      UniProtKB/TrEMBL
      D3Z6W7
      Related
      ENSMUSP00000081947.4, ENSMUST00000057896.5

    3. NM_001357006.1 → NP_001343935.1  glucoside xylosyltransferase 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC127360
      Consensus CDS
      CCDS88828.1
      UniProtKB/Swiss-Prot
      B7ZWC3, Q3UHH8
      Related
      ENSMUSP00000155854.2, ENSMUST00000230063.2
      Conserved Domains (1) summary
      cd06430
      Location:80 → 380
      GT8_like_2; GT8_like_2 represents a subfamily of GT8 with unknown function

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      93137611..93173060 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3UHH8.2 GenPept UniProtKB/Swiss-Prot:Q3UHH8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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