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    Slc25a34 solute carrier family 25, member 34 [ Mus musculus (house mouse) ]

    Gene ID: 384071, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Slc25a34provided by MGI
    Official Full Name
    solute carrier family 25, member 34provided by MGI
    Primary source
    MGI:MGI:2686215
    See related
    Ensembl:ENSMUSG00000040740 AllianceGenome:MGI:2686215
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm1369
    Summary
    Acts upstream of or within blastocyst hatching. Located in mitochondrion. Is expressed in early conceptus. Orthologous to human SLC25A34 (solute carrier family 25 member 34). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in heart adult (RPKM 69.7), colon adult (RPKM 20.1) and 5 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Slc25a34 in Genome Data Viewer
    Location:
    4 D3; 4 74.64 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (141346130..141351202, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (141618819..141623891, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1289 Neighboring gene STARR-positive B cell enhancer ABC_E1662 Neighboring gene filamin binding LIM protein 1 Neighboring gene STARR-seq mESC enhancer starr_11923 Neighboring gene expressed sequence AI507597 Neighboring gene STARR-positive B cell enhancer mm9_chr4:141180986-141181286 Neighboring gene transmembrane protein 82 Neighboring gene pleckstrin homology domain containing, family M (with RUN domain) member 2 Neighboring gene predicted gene, 54266 Neighboring gene STARR-seq mESC enhancer starr_11927 Neighboring gene regulatory solute carrier protein, family 1, member 1 Neighboring gene DNA-damage inducible protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Dysregulation of Lipid and Glucose Homeostasis in Hepatocyte-Specific SLC25A34 Knockout Mice. Roy N, et al. Am J Pathol, 2022 Sep. PMID 35718058, Free PMC Article
    2. Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. Cui W, et al. Sci Rep, 2016 Nov 21. PMID 27869233, Free PMC Article
    3. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    4. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
    5. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC107701

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within blastocyst hatching IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    solute carrier family 25 member 34

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013780.1 → NP_001013802.1  solute carrier family 25 member 34

      See identical proteins and their annotated locations for NP_001013802.1

      Status: PROVISIONAL

      Source sequence(s)
      AK142924, AL670446
      Consensus CDS
      CCDS18878.1
      UniProtKB/Swiss-Prot
      A2ADF7, Q5FW51
      Related
      ENSMUSP00000039188.8, ENSMUST00000038661.8
      Conserved Domains (1) summary
      pfam00153
      Location:217 → 309
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      141346130..141351202 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006538996.4 → XP_006539059.1  solute carrier family 25 member 34 isoform X1

      Conserved Domains (1) summary
      pfam00153
      Location:234 → 324
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2ADF7.1 GenPept UniProtKB/Swiss-Prot:A2ADF7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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