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    Or2ag2b olfactory receptor family 2 subfamily AG member 2B [ Mus musculus (house mouse) ]

    Gene ID: 66786, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Or2ag2bprovided by MGI
    Official Full Name
    olfactory receptor family 2 subfamily AG member 2Bprovided by MGI
    Primary source
    MGI:MGI:3030535
    See related
    Ensembl:ENSMUSG00000036744 AllianceGenome:MGI:3030535
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr701; MOR283-1; 4932441H21Rik; 4933433E02Rik
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Expression
    Restricted expression toward testis adult (RPKM 5.2) See more
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    Genomic context

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    See Or2ag2b in Genome Data Viewer
    Location:
    7 E3; 7 56.08 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (106413336..106419916)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (106814129..106820709)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily AG member 17 Neighboring gene olfactory receptor family 2 subfamily AG member 18 Neighboring gene olfactory receptor family 13 subfamily N member 4 Neighboring gene olfactory receptor family 2 subfamily AG member 19

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of novel post-transcriptional features in olfactory receptor family mRNAs. Shum EY, et al. Nucleic Acids Res, 2015 Oct 30. PMID 25908788, Free PMC Article
    2. Transcriptomes of mouse olfactory epithelium reveal sexual differences in odorant detection. Shiao MS, et al. Genome Biol Evol, 2012. PMID 22511034, Free PMC Article
    3. Update on the olfactory receptor (OR) gene superfamily. Olender T, et al. Hum Genomics, 2008 Sep. PMID 19129093, Free PMC Article
    4. Olfactory receptor genes expressed in distinct lineages are sequestered in different nuclear compartments. Yoon KH, et al. Proc Natl Acad Sci U S A, 2015 May 5. PMID 25897022, Free PMC Article
    5. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC123418

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor 701
    Names
    olfactory receptor MOR283-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360747.1 → NP_001347676.1  olfactory receptor 701

      Status: VALIDATED

      Source sequence(s)
      AC116327, AK016560, AK017036
      Consensus CDS
      CCDS21672.1
      UniProtKB/TrEMBL
      Q9D3U9, Q9D4F9
      Related
      ENSMUSP00000130958.2, ENSMUST00000166880.3
      Conserved Domains (1) summary
      cd15421
      Location:26 → 300
      7tmA_OR2T-like; olfactory receptor subfamily 2T and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. NM_028910.4 → NP_083186.2  olfactory receptor 701

      See identical proteins and their annotated locations for NP_083186.2

      Status: VALIDATED

      Source sequence(s)
      AK015248, AK016560, BC110461
      Consensus CDS
      CCDS21672.1
      UniProtKB/TrEMBL
      Q9D3U9, Q9D4F9
      Related
      ENSMUSP00000074868.2, ENSMUST00000075414.8
      Conserved Domains (1) summary
      cd15421
      Location:26 → 300
      7tmA_OR2T-like; olfactory receptor subfamily 2T and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      106413336..106419916
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017312235.1 → XP_017167724.1  olfactory receptor 701 isoform X1

      UniProtKB/TrEMBL
      Q9D3U9, Q9D4F9
      Conserved Domains (1) summary
      cd15421
      Location:26 → 300
      7tmA_OR2T-like; olfactory receptor subfamily 2T and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein Strain
    Heading Accession and Version

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