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    Tmsb15a thymosin beta 15a [ Mus musculus (house mouse) ]

    Gene ID: 78478, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmsb15aprovided by MGI
    Official Full Name
    thymosin beta 15aprovided by MGI
    Primary source
    MGI:MGI:1925728
    See related
    Ensembl:ENSMUSG00000060726 AllianceGenome:MGI:1925728
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tb15a; Tmsl8; Tmsbl1; 1700129I15Rik
    Summary
    Predicted to enable actin monomer binding activity. Predicted to be involved in regulation of cell migration and sequestering of actin monomers. Predicted to be active in cytoplasm. Is expressed in several structures, including heart; liver; lung; metanephros; and spleen. Orthologous to human TMSB15A (thymosin beta 15A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 4.8) See more
    Orthologs
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    Genomic context

    See Tmsb15a in Genome Data Viewer
    Location:
    X F1; X 57.26 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (134619416..134626010, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (135718667..135725261, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene PRAME like, X-linked 1 Neighboring gene NSA2 ribosome biogenesis homolog pseudogene Neighboring gene t-complex 11 family, X-linked 2 Neighboring gene STARR-seq mESC enhancer starr_47970 Neighboring gene G protein-coupled receptor associated sorting protein 1 Neighboring gene armadillo repeat containing, X-linked 5 Neighboring gene microRNA 7646 Neighboring gene RAB18, member RAS oncogene family pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin monomer binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in sequestering of actin monomers IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    thymosin beta-15A
    Names
    thymosin beta-like protein 1
    thymosin-like 8

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030106.3NP_084382.1  thymosin beta-15A

      See identical proteins and their annotated locations for NP_084382.1

      Status: VALIDATED

      Source sequence(s)
      AL671911
      Consensus CDS
      CCDS41130.1
      UniProtKB/TrEMBL
      Q9D2R9
      Related
      ENSMUSP00000073355.3, ENSMUST00000073674.3
      Conserved Domains (1) summary
      pfam01290
      Location:339
      Thymosin; Thymosin beta-4 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      134619416..134626010 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006528628.2XP_006528691.1  thymosin beta-15A isoform X1

      UniProtKB/TrEMBL
      A2AEH9
      Related
      ENSMUSP00000108779.2, ENSMUST00000113154.8
      Conserved Domains (1) summary
      pfam01290
      Location:3773
      Thymosin; Thymosin beta-4 family
    2. XM_006528629.2XP_006528692.1  thymosin beta-15A isoform X2

      See identical proteins and their annotated locations for XP_006528692.1

      UniProtKB/TrEMBL
      Q9D2R9
      Conserved Domains (1) summary
      pfam01290
      Location:339
      Thymosin; Thymosin beta-4 family