DAS2 putative uridine kinase DAS2 [Saccharomyces cerevisiae S288C] - Gene

Summary

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Official Symbol: DAS2
Official Full Name: putative uridine kinase DAS2
Primary source: SGD:S000002427
Locus tag: YDR020C
See related: AllianceGenome:SGD:S000002427; FungiDB:YDR020C; VEuPathDB:YDR020C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: RRT3
Summary: Predicted to enable ATP binding activity; cytidine kinase activity; and uridine kinase activity. Predicted to be involved in phosphorylation and pyrimidine ribonucleotide biosynthetic process. Located in cytoplasm and nucleus. Orthologous to human UCK1 (uridine-cytidine kinase 1) and UCK2 (uridine-cytidine kinase 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See DAS2 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 1

Sequence:: Chromosome: IV; NC_001136.10 (485746..486444, complement)

Chromosome IV - NC_001136.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables cytidine kinase activity	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info
enables uridine kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in CMP biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in CTP salvage	IEA Inferred from Electronic Annotation more info
involved_in UMP salvage	IEA Inferred from Electronic Annotation more info
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	HDA more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: putative uridine kinase DAS2

NP_010303.3

EC 2.7.1.48

hypothetical protein; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; weak similarity with uridine kinases and with phosphoribokinases

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001136.10 Reference assembly

Range

485746..486444 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001180328.3 → NP_010303.3 TPA: putative uridine kinase DAS2 [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_010303.3

Status: REVIEWED

UniProtKB/Swiss-Prot

D6VS06, Q12084

UniProtKB/TrEMBL

A6ZXY4, B3LGP4, B5VFS8, C7GLX6, C8Z4U0, G2WAC7, N1PAB7

Conserved Domains (1) summary

COG0572
Location:8 → 209

Udk; Uridine kinase [Nucleotide transport and metabolism]