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    TEA1 Tea1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854515, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TEA1
    Official Full Name
    Tea1p
    Primary source
    SGD:S000005864
    Locus tag
    YOR337W
    See related
    AllianceGenome:SGD:S000005864; FungiDB:YOR337W; VEuPathDB:YOR337W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables DNA binding activity. Involved in transcription elongation by RNA polymerase II. Located in cell cortex of cell tip. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See TEA1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (954344..956623)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene alanine--tRNA ligase Neighboring gene Kre5p Neighboring gene uncharacterized protein Neighboring gene putative E2 ubiquitin-protein ligase UBC11

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation and analysis of the yeast TEA1 gene, which encodes a zinc cluster Ty enhancer-binding protein. Gray WM, et al. Mol Cell Biol, 1996 Jan. PMID 8524314, Free PMC Article
    2. Spatial segregation of polarity factors into distinct cortical clusters is required for cell polarity control. Dodgson J, et al. Nat Commun, 2013. PMID 23673619, Free PMC Article
    3. Identification of the Sin3-binding site in Ume6 defines a two-step process for conversion of Ume6 from a transcriptional repressor to an activator in yeast. Washburn BK, et al. Mol Cell Biol, 2001 Mar. PMID 11238941, Free PMC Article
    4. A phenotypic profile of the Candida albicans regulatory network. Homann OR, et al. PLoS Genet, 2009 Dec. PMID 20041210, Free PMC Article
    5. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Badis G, et al. Mol Cell, 2008 Dec 26. PMID 19111667, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding HDA PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription elongation by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell cortex of cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Tea1p
    NP_014982.3
    • Ty1 enhancer activator involved in Ty enhancer-mediated transcription; required for full levels of Ty enhancer-mediated transcription; C6 zinc cluster DNA-binding protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      954344..956623
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183757.3 → NP_014982.3  TPA: Tea1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014982.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W332, P47988
      UniProtKB/TrEMBL
      B3LJZ6, B5VSL5, N1NXH8
      Conserved Domains (2) summary
      smart00066
      Location:64 → 105
      GAL4; GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain
      pfam04082
      Location:329 → 579
      Fungal_trans; Fungal specific transcription factor domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47988.2

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