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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029511.1 RefSeqGene
- Range
-
5043..183795
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001316676.2 → NP_001303605.1 receptor-type tyrosine-protein phosphatase epsilon isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) encodes isoform 3.
- Source sequence(s)
-
AF406557, AK026334, AL390236, BC031078, BC050062, BC071573, X54134
- UniProtKB/TrEMBL
-
A8K2Z9
- Conserved Domains (2) summary
-
- smart00194
Location:145 → 404
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:172 → 404
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
-
NM_001316677.2 → NP_001303606.1 receptor-type tyrosine-protein phosphatase epsilon isoform 1 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) contains an alternate 5' exon in place of the first 3 exons and lacks a large part of the 3' UTR compared to variant 3. The resulting isoform (1) is shorter at the N-terminus compared to isoform 3. The encoded protein is a receptor type isoform of this PTP. Variants 1, 4, and 5 all encode the same isoform (1).
- Source sequence(s)
-
AK026334, AK291828, BC071573
- Consensus CDS
-
CCDS7657.1
- UniProtKB/Swiss-Prot
- P23469, Q13345, Q5VWH3, Q5VWH4, Q96KQ6
- UniProtKB/TrEMBL
-
A8K2Z9
- Conserved Domains (2) summary
-
- smart00194
Location:134 → 393
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:453 → 688
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
-
NM_001323354.2 → NP_001310283.1 receptor-type tyrosine-protein phosphatase epsilon isoform 1 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (5), along with variants 1 and 4, encodes isoform 1.
- Source sequence(s)
-
AL390236
- Consensus CDS
-
CCDS7657.1
- UniProtKB/Swiss-Prot
- P23469, Q13345, Q5VWH3, Q5VWH4, Q96KQ6
- UniProtKB/TrEMBL
-
A8K2Z9
- Conserved Domains (2) summary
-
- smart00194
Location:134 → 393
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:453 → 688
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
-
NM_001323355.2 → NP_001310284.1 receptor-type tyrosine-protein phosphatase epsilon isoform 4 precursor
Status: REVIEWED
- Source sequence(s)
-
AL158166, AL390236
- UniProtKB/TrEMBL
-
A8K2Z9
- Conserved Domains (2) summary
-
- smart00194
Location:154 → 413
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:181 → 413
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
-
NM_001323356.2 → NP_001310285.1 receptor-type tyrosine-protein phosphatase epsilon isoform 5 precursor
Status: REVIEWED
- Source sequence(s)
-
AL158166, AL390236
- UniProtKB/TrEMBL
-
A8K2Z9
-
NM_001323357.2 → NP_001310286.1 receptor-type tyrosine-protein phosphatase epsilon isoform 6
Status: REVIEWED
- Source sequence(s)
-
AL390236
- Conserved Domains (1) summary
-
- cl28904
Location:260 → 469
- PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
-
NM_006504.6 → NP_006495.1 receptor-type tyrosine-protein phosphatase epsilon isoform 1 precursor
See identical proteins and their annotated locations for NP_006495.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) lacks a 5' exon compared to variant 3. The resulting isoform (1) is shorter at the N-terminus compared to isoform 3. The encoded protein is a receptor type isoform of this PTP. Variants 1, 4, and 5 all encode the same isoform (1).
- Source sequence(s)
-
AF406557, AK026334, AL390236, BC031078, BC071573, X54134
- Consensus CDS
-
CCDS7657.1
- UniProtKB/Swiss-Prot
- P23469, Q13345, Q5VWH3, Q5VWH4, Q96KQ6
- UniProtKB/TrEMBL
-
A8K2Z9
- Related
- ENSP00000254667.3, ENST00000254667.8
- Conserved Domains (2) summary
-
- smart00194
Location:134 → 393
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:453 → 688
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
-
NM_130435.5 → NP_569119.1 receptor-type tyrosine-protein phosphatase epsilon isoform 2
See identical proteins and their annotated locations for NP_569119.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) contains an alternate exon in place of the first 5 exons compared to variant 3. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 3. The encoded protein is a cytoplasmic isoform of this PTP.
- Source sequence(s)
-
AK026334, AK290414, AL390236, BC071573, DA470230
- Consensus CDS
-
CCDS7658.1
- UniProtKB/TrEMBL
-
A8K2Z9
- Related
- ENSP00000303350.5, ENST00000306042.9
- Conserved Domains (2) summary
-
- smart00194
Location:76 → 335
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:103 → 335
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000010.11 Reference GRCh38.p14 Primary Assembly
- Range
-
127907103..128085855
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047425578.1 → XP_047281534.1 receptor-type tyrosine-protein phosphatase epsilon isoform X7
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_017016467.2 → XP_016871956.1 receptor-type tyrosine-protein phosphatase epsilon isoform X1
- UniProtKB/TrEMBL
-
A8K2Z9
- Conserved Domains (2) summary
-
- smart00194
Location:154 → 413
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:181 → 413
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
-
XM_011539995.2 → XP_011538297.1 receptor-type tyrosine-protein phosphatase epsilon isoform X3
- UniProtKB/TrEMBL
-
B4DUE5
- Conserved Domains (2) summary
-
- smart00194
Location:154 → 413
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:181 → 413
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
-
XM_011539996.2 → XP_011538298.1 receptor-type tyrosine-protein phosphatase epsilon isoform X4
- UniProtKB/TrEMBL
-
A8K2Z9
- Conserved Domains (2) summary
-
- smart00194
Location:154 → 413
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:181 → 413
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
-
XM_011539994.3 → XP_011538296.1 receptor-type tyrosine-protein phosphatase epsilon isoform X2
- UniProtKB/TrEMBL
-
A8K2Z9
- Conserved Domains (2) summary
-
- smart00194
Location:154 → 412
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:181 → 412
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
-
XM_017016469.3 → XP_016871958.1 receptor-type tyrosine-protein phosphatase epsilon isoform X12
-
XM_011539998.2 → XP_011538300.1 receptor-type tyrosine-protein phosphatase epsilon isoform X14
- Conserved Domains (2) summary
-
- smart00194
Location:154 → 355
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:181 → 355
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
-
XM_047425577.1 → XP_047281533.1 receptor-type tyrosine-protein phosphatase epsilon isoform X5
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_047425576.1 → XP_047281532.1 receptor-type tyrosine-protein phosphatase epsilon isoform X16
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_005252691.3 → XP_005252748.1 receptor-type tyrosine-protein phosphatase epsilon isoform X6
See identical proteins and their annotated locations for XP_005252748.1
- UniProtKB/Swiss-Prot
- P23469, Q13345, Q5VWH3, Q5VWH4, Q96KQ6
- UniProtKB/TrEMBL
-
A8K2Z9
- Conserved Domains (2) summary
-
- smart00194
Location:134 → 393
- PTPc; Protein tyrosine phosphatase, catalytic domain
- cd00047
Location:453 → 688
- PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
-
XM_047425582.1 → XP_047281538.1 receptor-type tyrosine-protein phosphatase epsilon isoform X11
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_047425579.1 → XP_047281535.1 receptor-type tyrosine-protein phosphatase epsilon isoform X8
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_047425580.1 → XP_047281536.1 receptor-type tyrosine-protein phosphatase epsilon isoform X9
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_047425581.1 → XP_047281537.1 receptor-type tyrosine-protein phosphatase epsilon isoform X10
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_047425583.1 → XP_047281539.1 receptor-type tyrosine-protein phosphatase epsilon isoform X13
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_047425584.1 → XP_047281540.1 receptor-type tyrosine-protein phosphatase epsilon isoform X15
Alternate T2T-CHM13v2.0
Genomic
-
NC_060934.1 Alternate T2T-CHM13v2.0
- Range
-
128805632..128984409
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054366446.1 → XP_054222421.1 receptor-type tyrosine-protein phosphatase epsilon isoform X7
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_054366440.1 → XP_054222415.1 receptor-type tyrosine-protein phosphatase epsilon isoform X1
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_054366442.1 → XP_054222417.1 receptor-type tyrosine-protein phosphatase epsilon isoform X3
- UniProtKB/TrEMBL
-
B4DUE5
-
XM_054366443.1 → XP_054222418.1 receptor-type tyrosine-protein phosphatase epsilon isoform X4
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_054366441.1 → XP_054222416.1 receptor-type tyrosine-protein phosphatase epsilon isoform X2
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_054366451.1 → XP_054222426.1 receptor-type tyrosine-protein phosphatase epsilon isoform X12
-
XM_054366453.1 → XP_054222428.1 receptor-type tyrosine-protein phosphatase epsilon isoform X14
-
XM_054366444.1 → XP_054222419.1 receptor-type tyrosine-protein phosphatase epsilon isoform X5
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_054366445.1 → XP_054222420.1 receptor-type tyrosine-protein phosphatase epsilon isoform X6
- UniProtKB/Swiss-Prot
- P23469, Q13345, Q5VWH3, Q5VWH4, Q96KQ6
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_054366450.1 → XP_054222425.1 receptor-type tyrosine-protein phosphatase epsilon isoform X11
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_054366447.1 → XP_054222422.1 receptor-type tyrosine-protein phosphatase epsilon isoform X8
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_054366448.1 → XP_054222423.1 receptor-type tyrosine-protein phosphatase epsilon isoform X9
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_054366449.1 → XP_054222424.1 receptor-type tyrosine-protein phosphatase epsilon isoform X10
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_054366452.1 → XP_054222427.1 receptor-type tyrosine-protein phosphatase epsilon isoform X13
- UniProtKB/TrEMBL
-
A8K2Z9
-
XM_054366454.1 → XP_054222429.1 receptor-type tyrosine-protein phosphatase epsilon isoform X15