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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001173513.3 → NP_001166984.1 thioredoxin reductase 3 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1, which results in a shorter isoform (2) missing an internal protein segment compared to isoform 1. A non-AUG (CUG) codon is used as translation initiation codon.
- Source sequence(s)
-
AC024558
- Consensus CDS
-
CCDS77810.1
- UniProtKB/TrEMBL
-
H0YBI6
- Related
- ENSP00000429584.3, ENST00000523403.3
- Conserved Domains (4) summary
-
- cd03419
Location:67 → 148
- GRX_GRXh_1_2_like; Glutaredoxin (GRX) family, GRX human class 1 and 2 (h_1_2)-like subfamily; composed of proteins similar to human GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, ...
- TIGR01438
Location:155 → 607
- TGR; thioredoxin and glutathione reductase selenoprotein
- pfam00070
Location:336 → 412
- Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
- pfam02852
Location:508 → 589
- Pyr_redox_dim; Pyridine nucleotide-disulphide oxidoreductase, dimerization domain
-
NM_052883.3 → NP_443115.1 thioredoxin reductase 3 isoform 1
See identical proteins and their annotated locations for NP_443115.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longer isoform (1). A non-AUG (CUG) codon is used as translation initiation codon.
- Source sequence(s)
-
AC024558
- Consensus CDS
-
CCDS77811.1
- UniProtKB/Swiss-Prot
- Q6F5E7, Q6PIS8, Q86VQ6, Q9NNW6, Q9P101
- UniProtKB/TrEMBL
-
H0YBQ0
- Related
- ENSP00000430031.4, ENST00000524230.9
- Conserved Domains (4) summary
-
- cd03419
Location:67 → 148
- GRX_GRXh_1_2_like; Glutaredoxin (GRX) family, GRX human class 1 and 2 (h_1_2)-like subfamily; composed of proteins similar to human GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, ...
- TIGR01438
Location:155 → 643
- TGR; thioredoxin and glutathione reductase selenoprotein
- pfam00070
Location:336 → 412
- Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
- pfam02852
Location:515 → 625
- Pyr_redox_dim; Pyridine nucleotide-disulphide oxidoreductase, dimerization domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000003.12 Reference GRCh38.p14 Primary Assembly
- Range
-
126607050..126655124 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060927.1 Alternate T2T-CHM13v2.0
- Range
-
129339825..129387575 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001039783.1: Suppressed sequence
- Description
- NM_001039783.1: This RefSeq was removed because currently there is support for the transcript but not for the protein.