Cyria CYFIP related Rac1 interactor A [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cyriaprovided by MGI
Official Full Name: CYFIP related Rac1 interactor Aprovided by MGI
Primary source: MGI:MGI:1261783
See related: Ensembl:ENSMUSG00000020589 AllianceGenome:MGI:1261783
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Fam49a; 9630047E15; D12Ertd553e; 2410157M17Rik
Summary: Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of actin filament polymerization. Predicted to be located in membrane. Is expressed in cerebral cortex intermediate zone; cerebral cortex mantle layer; cortical plate; olfactory cortex mantle layer; and thalamus mantle layer. Orthologous to human CYRIA (CYFIP related Rac1 interactor A). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Broad expression in CNS E18 (RPKM 20.0), frontal lobe adult (RPKM 15.6) and 15 other tissues See more
Orthologs: human all
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Genomic context

Location:: 12 A1.1; 12 5.63 cM

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	12	NC_000078.7 (12312136..12430966)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	12	NC_000078.6 (12262134..12380965)

Chromosome 12 - NC_000078.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

BE686334 (e-PCR)
- UniSTS:208781

D12Mit56 (e-PCR), detects polymorphism
- UniSTS:126877

AU022673 (e-PCR)
- UniSTS:167094

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables small GTPase binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in regulation of actin filament polymerization	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: CYFIP-related Rac1 interactor A

Names: family with sequence similarity 49, member A; family with sequence similarity 49, member B; protein FAM49A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.