U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    lit cell death peptidase Lit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948421, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    lit
    Official Full Name
    cell death peptidase Lit
    Primary source
    ECOCYC:EG10535
    Locus tag
    b1139
    See related
    ASAP:ABE-0003834
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1125
    Summary
    The lit gene is part of the defective prophage element e14 . [More information is available at EcoCyc: EG10535].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (1198695..1199588)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative SAM-dependent methyltransferase YmfD Neighboring gene uncharacterized protein YmfE Neighboring gene putative integrase Neighboring gene putative excisionase Neighboring gene putative protein YmfH

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A new gene of Escherichia coli K-12 whose product participates in T4 bacteriophage late gene expression: interaction of lit with the T4-induced polynucleotide 5'-kinase 3'-phosphatase. Cooley W, et al. J Bacteriol, 1979 Oct. PMID 227837, Free PMC Article
    2. A site in the T4 bacteriophage major head protein gene that can promote the inhibition of all translation in Escherichia coli. Bergsland KJ, et al. J Mol Biol, 1990 Jun 5. PMID 2191141
    3. Identification of essential residues within Lit, a cell death peptidase of Escherichia coli K-12. Copeland NA, et al. Biochemistry, 2004 Jun 22. PMID 15196039
    4. The lit gene product which blocks bacteriophage T4 late gene expression is a membrane protein encoded by a cryptic DNA element, e14. Kao C, et al. J Bacteriol, 1988 May. PMID 2452152, Free PMC Article
    5. Cloning and characterization of the Escherichia coli lit gene, which blocks bacteriophage T4 late gene expression. Kao C, et al. J Bacteriol, 1987 Mar. PMID 3546267, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. phage-elicited suicide of E. coli K-12 by Lit is a variant form of "cofactor-induced activation"
      Title: The role of an activating peptide in protease-mediated suicide of Escherichia coli K12.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables peptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of translational elongation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    cell death peptidase Lit

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1198695..1199588
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415657.1 cell death peptidase Lit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415657.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P11072
      Conserved Domains (1) summary
      PRK09672
      Location:1 → 293
      PRK09672; phage exclusion protein Lit; Provisional
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.