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    fepC ferric enterobactin ABC transporter ATP binding subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945201, updated on 3-Dec-2024

    Summary

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    Official Symbol
    fepC
    Official Full Name
    ferric enterobactin ABC transporter ATP binding subunit
    Primary source
    ECOCYC:EG10295
    Locus tag
    b0588
    See related
    ASAP:ABE-0002025
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0581
    Summary
    FepBCDG are components of a ferric enterobactin transport complex that is a member of the ATP-binding cassette (ABC) family of transporters. [More information is available at EcoCyc: EG10295].
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    Genomic context

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    Sequence:
    NC_000913.3 (619384..620199, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene ferric enterobactin esterase Neighboring gene enterobactin biosynthesis protein YbdZ Neighboring gene apo-serine activating enzyme Neighboring gene polysaccharide co-polymerase family protein FepE Neighboring gene ferric enterobactin ABC transporter membrane subunit FepG Neighboring gene ferric enterobactin ABC transporter membrane subunit FebD Neighboring gene enterobactin exporter EntS

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Escherichia coli K-12 envelope proteins specifically required for ferrienterobactin uptake. Pierce JR, et al. J Bacteriol, 1986 Jun. PMID 3011753, Free PMC Article
    2. Binding of ferric enterobactin by the Escherichia coli periplasmic protein FepB. Sprencel C, et al. J Bacteriol, 2000 Oct. PMID 10986237, Free PMC Article
    3. Fur-DNA interactions at the bidirectional fepDGC-entS promoter region in Escherichia coli. Lavrrar JL, et al. J Mol Biol, 2002 Oct 4. PMID 12367523
    4. Mutations in the Escherichia coli receptor FepA reveal residues involved in ligand binding and transport. Barnard TJ, et al. Mol Microbiol, 2001 Aug. PMID 11532122
    5. Escherichia coli periplasmic protein FepB binds ferrienterobactin. Stephens DL, et al. Microbiology (Reading), 1995 Jul. PMID 7551033

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ferric-enterobactin transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within ferric-enterobactin import into cell IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in iron import into cell NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in iron ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ATP-binding cassette (ABC) transporter complex RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ferric enterobactin ABC transporter ATP binding subunit
    NP_415120.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      619384..620199 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415120.1 ferric enterobactin ABC transporter ATP binding subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415120.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A7A2XXE8, A0A8S7EIJ9
      Conserved Domains (1) summary
      PRK10253
      Location:1 → 265
      PRK10253; iron-enterobactin ABC transporter ATP-binding protein
    Nucleotide Protein
    Heading Accession and Version

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