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    dgcP diguanylate cyclase DgcP [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948969, updated on 17-Dec-2024

    Summary

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    Official Symbol
    dgcP
    Official Full Name
    diguanylate cyclase DgcP
    Primary source
    ECOCYC:G6980
    Locus tag
    b1794
    See related
    ASAP:ABE-0005972
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1792; yeaP
    Summary
    YeaP has diguanylate cyclase activity in vitro (Ryjenkov, 2005). [More information is available at EcoGene: EG13502]. YeaP is a GGDEF domain-containing protein that has diguanylate cyclase activity . [More information is available at EcoCyc: G6980].
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    Genomic context

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    Sequence:
    NC_000913.3 (1877715..1878740)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF488 domain-containing protein YeaO Neighboring gene DUF333 domain-containing lipoprotein YoaF Neighboring gene putative membrane protein YoaK Neighboring gene uncharacterized protein YoaJ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Bacterial nucleotide-based second messengers. Pesavento C, et al. Curr Opin Microbiol, 2009 Apr. PMID 19318291
    2. Cyclic diguanylate is a ubiquitous signaling molecule in bacteria: insights into biochemistry of the GGDEF protein domain. Ryjenkov DA, et al. J Bacteriol, 2005 Mar. PMID 15716451, Free PMC Article
    3. C-di-GMP: the dawning of a novel bacterial signalling system. Römling U, et al. Mol Microbiol, 2005 Aug. PMID 16045609
    4. Gene expression patterns and differential input into curli fimbriae regulation of all GGDEF/EAL domain proteins in Escherichia coli. Sommerfeldt N, et al. Microbiology (Reading), 2009 Apr. PMID 19332833
    5. Characterization of the rdar morphotype, a multicellular behaviour in Enterobacteriaceae. Römling U. Cell Mol Life Sci, 2005 Jun. PMID 15818467, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables diguanylate cyclase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables diguanylate cyclase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables diguanylate cyclase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell adhesion involved in single-species biofilm formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of bacterial-type flagellum-dependent cell motility IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    diguanylate cyclase DgcP
    NP_416308.4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1877715..1878740
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416308.4 diguanylate cyclase DgcP [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416308.4

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A1V2G7M9
      Conserved Domains (2) summary
      smart00065
      Location:19 → 164
      GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
      pfam00990
      Location:174 → 329
      GGDEF; Diguanylate cyclase, GGDEF domain
    Nucleotide Protein
    Heading Accession and Version

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