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    chiA endochitinase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947837, updated on 3-Dec-2024

    Summary

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    Official Symbol
    chiA
    Official Full Name
    endochitinase
    Primary source
    ECOCYC:EG11237
    Locus tag
    b3338
    See related
    ASAP:ABE-0010909
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3325; yheB
    Summary
    A purified fragment of ChiA binds to chitin with high affinity, but binds only poorly to cellulose . [More information is available at EcoCyc: EG11237].
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    Genomic context

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    Sequence:
    NC_000913.3 (3467160..3469853, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene bacterioferritin Neighboring gene bacterioferritin-associated ferredoxin Neighboring gene translation elongation factor Tu 1 Neighboring gene elongation factor G

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of the carbohydrate-binding domains of Erwinia chrysanthemi Cel5 (Endoglucanase Z) and an Escherichia coli putative chitinase. Simpson HD, et al. J Bacteriol, 1999 Aug. PMID 10419961, Free PMC Article
    2. Chitin, Chitin Oligosaccharide, and Chitin Disaccharide Metabolism of Escherichia coli Revisited: Reassignment of the Roles of ChiA, ChbR, ChbF, and ChbG. Walter A, et al. Microb Physiol, 2021. PMID 33794535
    3. The ChiA (YheB) protein of Escherichia coli K-12 is an endochitinase whose gene is negatively controlled by the nucleoid-structuring protein H-NS. Francetic O, et al. Mol Microbiol, 2000 Mar. PMID 10760150
    4. Cloning, sequencing, and mapping of the bacterioferritin gene (bfr) of Escherichia coli K-12. Andrews SC, et al. J Bacteriol, 1989 Jul. PMID 2661540, Free PMC Article
    5. Role of the Escherichia coli Tat pathway in outer membrane integrity. Ize B, et al. Mol Microbiol, 2003 Jun. PMID 12787348

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chitin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables endochitinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables endochitinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables endochitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, acting on glycosyl bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lysozyme activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chitin catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in polysaccharide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in outer membrane-bounded periplasmic space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in outer membrane-bounded periplasmic space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in periplasmic space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    endochitinase
    NP_417797.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3467160..3469853 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417797.1 endochitinase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417797.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0AAI9MEB6
      Conserved Domains (3) summary
      cd06543
      Location:587 → 892
      GH18_PF-ChiA-like; PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain. Members of this domain family are found not only in ...
      smart00495
      Location:128 → 173
      ChtBD3; Chitin-binding domain type 3
      cd12215
      Location:461 → 509
      ChiC_BD; Chitin-binding domain of chitinase C
    Nucleotide Protein
    Heading Accession and Version

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