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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001081155.4 → NP_001074624.1 rap1 GTPase-activating protein 1 isoform 1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1.
- Source sequence(s)
-
AL805954
- Consensus CDS
-
CCDS38925.1
- UniProtKB/Swiss-Prot
-
A2ALS5
- Related
- ENSMUSP00000042473.6, ENSMUST00000047243.12
- Conserved Domains (2) summary
-
- smart00390
Location:61 → 81
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- pfam02145
Location:275 → 454
- Rap_GAP; Rap/ran-GAP
-
NM_001256218.2 → NP_001243147.1 rap1 GTPase-activating protein 1 isoform 2
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) uses two different splice sites in the 3' coding region which shifts the reading frame, compared to variant 1. The resulting protein (isoform 2) has a longer and distinct C-terminus when it is compared to isoform 1.
- Source sequence(s)
-
AL805954
- Consensus CDS
-
CCDS57306.1
- UniProtKB/TrEMBL
-
A2ALS4
- Related
- ENSMUSP00000101461.2, ENSMUST00000105835.8
- Conserved Domains (2) summary
-
- smart00390
Location:61 → 81
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- pfam02145
Location:275 → 454
- Rap_GAP; Rap/ran-GAP
-
NM_001331215.2 → NP_001318144.1 rap1 GTPase-activating protein 1 isoform 4
Status: VALIDATED
- Description
- Transcript Variant: This variant (5) represents use of an alternate promoter and differs in the 5' UTR and 5' coding region compared to variant 1. The encoded isoform (4) has a shorter, distinct N-terminus compared to isoform 1.
- Source sequence(s)
-
AL805954
- Consensus CDS
-
CCDS84809.1
- UniProtKB/Swiss-Prot
-
A2ALS5
- Related
- ENSMUSP00000095448.5, ENSMUST00000097837.11
-
NM_001379233.1 → NP_001366162.1 rap1 GTPase-activating protein 1 isoform 5
Status: VALIDATED
- Source sequence(s)
-
AL805954
- Conserved Domains (2) summary
-
- smart00390
Location:61 → 81
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- pfam02145
Location:275 → 454
- Rap_GAP; Rap/ran-GAP
-
NM_001379234.1 → NP_001366163.1 rap1 GTPase-activating protein 1 isoform 6
Status: VALIDATED
- Source sequence(s)
-
AL805954
- Conserved Domains (2) summary
-
- smart00390
Location:28 → 48
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- pfam02145
Location:242 → 421
- Rap_GAP; Rap/ran-GAP
-
NM_001379235.1 → NP_001366164.1 rap1 GTPase-activating protein 1 isoform 7
Status: VALIDATED
- Source sequence(s)
-
AL805954
- Conserved Domains (2) summary
-
- smart00390
Location:49 → 69
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- pfam02145
Location:263 → 442
- Rap_GAP; Rap/ran-GAP
-
NM_001379236.1 → NP_001366165.1 rap1 GTPase-activating protein 1 isoform 8
Status: VALIDATED
- Source sequence(s)
-
AL805954
- Conserved Domains (2) summary
-
- smart00390
Location:1 → 17
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- pfam02145
Location:211 → 390
- Rap_GAP; Rap/ran-GAP
-
NM_029563.3 → NP_083839.1 rap1 GTPase-activating protein 1 isoform 3
See identical proteins and their annotated locations for NP_083839.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) represents use of an alternate promoter and initiates translation at a downstream start codon, compared to variant 1. The encoded protein (isoform 3) is shorter when it is compared to isoform 1.
- Source sequence(s)
-
AL805954
- UniProtKB/Swiss-Prot
- A2ALS5, E9PZZ8, Q6A063, Q80VZ8, Q8K2L6
- Conserved Domains (2) summary
-
- pfam02145
Location:211 → 390
- Rap_GAP; Rap/ran-GAP
- pfam02188
Location:1 → 17
- GoLoco; GoLoco motif
RNA
-
NR_138591.1 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) represents use of an alternate promoter and uses an alternate splice site compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AL805954
-
NR_138592.1 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (6) represents use of an alternate promoter, differs in the 5' region, and uses an alternate splice site in the 3' region, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AK005063, AK019076