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    Spata4 spermatogenesis associated 4 [ Mus musculus (house mouse) ]

    Gene ID: 69281, updated on 9-Dec-2024

    Summary

    Official Symbol
    Spata4provided by MGI
    Official Full Name
    spermatogenesis associated 4provided by MGI
    Primary source
    MGI:MGI:1916531
    See related
    Ensembl:ENSMUSG00000031518 AllianceGenome:MGI:1916531
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Srg2; TSARG2; 1700001N01Rik
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in regulation of cytoskeleton organization. Located in cytoplasm. Orthologous to human SPATA4 (spermatogenesis associated 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 240.1) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Spata4 in Genome Data Viewer
    Location:
    8 B1.3; 8 29.27 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (55053816..55063133)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (54600781..54610098)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 5330439A09 gene Neighboring gene ankyrin repeat and SOCs box-containing 5 Neighboring gene STARR-seq mESC enhancer starr_21499 Neighboring gene predicted gene, 46039 Neighboring gene STARR-seq mESC enhancer starr_21500 Neighboring gene WD repeat domain 17 Neighboring gene STARR-seq mESC enhancer starr_21502 Neighboring gene glycoprotein m6a Neighboring gene predicted gene, 53418

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2)  1 citation

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in regulation of cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in axoneme IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    spermatogenesis-associated protein 4
    Names
    spermatogenesis-related gene 2 protein
    testis and spermatogenesis cell-related protein 2
    testis spermatocyte apoptosis-related gene 2 protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133711.4NP_598472.2  spermatogenesis-associated protein 4

      See identical proteins and their annotated locations for NP_598472.2

      Status: VALIDATED

      Source sequence(s)
      AC102933
      Consensus CDS
      CCDS22308.1
      UniProtKB/Swiss-Prot
      Q8K3V1, Q923U8
      Related
      ENSMUSP00000033917.7, ENSMUST00000033917.7
      Conserved Domains (1) summary
      pfam06294
      Location:55144
      CH_2; CH-like domain in sperm protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      55053816..55063133
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)