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    Igkv1-110 immunoglobulin kappa variable 1-110 [ Mus musculus (house mouse) ]

    Gene ID: 381777, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Igkv1-110provided by MGI
    Official Full Name
    immunoglobulin kappa variable 1-110provided by MGI
    Primary source
    MGI:MGI:4439558
    See related
    Ensembl:ENSMUSG00000093861 IMGT/GENE-DB:IGKV1-110; AllianceGenome:MGI:4439558
    Gene type
    other
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Igk; K5.1; Gm16634
    Summary
    Predicted to be involved in immune response. Predicted to be part of immunoglobulin complex. Orthologous to several human genes including IGKV2-29 (immunoglobulin kappa variable 2-29) and IGKV2D-29 (immunoglobulin kappa variable 2D-29). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Igkv1-110 in Genome Data Viewer
    Location:
    6 C1; 6 31.12 cM
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (68247511..68248249)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (68270527..68271265)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin kappa chain complex Neighboring gene STARR-positive B cell enhancer mm9_chr6:68252207-68252508 Neighboring gene immunoglobulin kappa variable 14-111 Neighboring gene immunoglobulin kappa variable 2-109 Neighboring gene immunoglobulin kappa variable 1-108 Neighboring gene predicted gene, 25436

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Active site structure and antigen binding properties of idiotypically cross-reactive anti-fluorescein monoclonal antibodies. Bedzyk WD, et al. J Biol Chem, 1990 Jan 5. PMID 2104617
    2. Nucleotide and translated amino acid sequences of cDNA coding for the variable regions of the light and heavy chains of mouse hybridoma antibodies to blood group A and B substances. Chen HT, et al. J Biol Chem, 1987 Oct 5. PMID 3115981
    3. Two V kappa germ-line genes related to the GAT idiotypic network (Ab1 and Ab3/Ab1') account for the major subfamilies of the mouse V kappa-1 variability subgroup. Corbet S, et al. J Immunol, 1987 Feb 1. PMID 3100621
    4. Immunoglobulin kappa light chain variable region gene complex organization and immunoglobulin genes encoding anti-DNA autoantibodies in lupus mice. Kofler R, et al. J Clin Invest, 1988 Sep. PMID 3138286, Free PMC Article
    5. Genes coding evolutionary novel anti-carbohydrate antibodies: studies on anti-Gal production in alpha 1,3galactosyltransferase knock out mice. Chen ZC, et al. Mol Immunol, 2000 Jun. PMID 11090880

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Other Names

    • anti-fluorescein antibody
    • immunoglobulin kappa chain variable 1-110

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of immunoglobulin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_005612.1 

      Range
      715547..716285
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      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      68247511..68248249
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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