Eif3g eukaryotic translation initiation factor 3, subunit G [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Eif3gprovided by MGI
Official Full Name: eukaryotic translation initiation factor 3, subunit Gprovided by MGI
Primary source: MGI:MGI:1858258
See related: Ensembl:ENSMUSG00000070319 AllianceGenome:MGI:1858258
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: p44; 44kDa; D0Jmb4; Eif3s4; TU-189B2; eIF3-p44
Summary: Contributes to translation initiation factor activity. Involved in translational initiation. Part of eukaryotic translation initiation factor 3 complex. Is expressed in embryo. Orthologous to human EIF3G (eukaryotic translation initiation factor 3 subunit G). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in testis adult (RPKM 95.4), placenta adult (RPKM 70.7) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 9 A3; 9 7.66 cM

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (20805645..20809886, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (20894349..20898590, complement)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables RNA binding	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
contributes_to translation initiation factor activity	IDA Inferred from Direct Assay more info	PubMed
contributes_to translation initiation factor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in formation of cytoplasmic translation initiation complex	IEA Inferred from Electronic Annotation more info
involved_in translational initiation	IDA Inferred from Direct Assay more info	PubMed
involved_in translational initiation	ISO Inferred from Sequence Orthology more info
involved_in viral translational termination-reinitiation	IEA Inferred from Electronic Annotation more info
involved_in viral translational termination-reinitiation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
part_of eukaryotic 43S preinitiation complex	IEA Inferred from Electronic Annotation more info
part_of eukaryotic 48S preinitiation complex	IEA Inferred from Electronic Annotation more info
part_of eukaryotic translation initiation factor 3 complex	IDA Inferred from Direct Assay more info	PubMed
part_of eukaryotic translation initiation factor 3 complex	ISO Inferred from Sequence Orthology more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in perinuclear region of cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: eukaryotic translation initiation factor 3 subunit G

Names: eIF-3 RNA-binding subunit; eIF-3-delta; eIF3 p42; eIF3 p44; eiF3 delta; eukaryotic translation initiation factor 3 RNA-binding subunit; eukaryotic translation initiation factor 3 subunit 4; eukaryotic translation initiation factor 3, subunit 4 (delta); eukaryotic translation initiation factor 3, subunit 4 (delta, 44 kDa); eukaryotic translation initiation factor 3, subunit 4 (delta, 44kD); eukaryotic translation initiation factor 3 subunit p42; translation initiation factor eIF3-p44

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_016876.3 → NP_058572.2 eukaryotic translation initiation factor 3 subunit G

See identical proteins and their annotated locations for NP_058572.2

Status: PROVISIONAL

Source sequence(s)

AC170598

Consensus CDS

CCDS40547.1

UniProtKB/Swiss-Prot

Q9R079, Q9Z1D1

UniProtKB/TrEMBL

Q3THA0, Q544H0

Related

ENSMUSP00000004206.9, ENSMUST00000004206.10

Conserved Domains (2) summary

cd12933
Location:62 → 173

eIF3G; eIF3G domain found in eukaryotic translation initiation factor 3 subunit G (eIF-3G) and similar proteins

cd12408
Location:240 → 316

RRM_eIF3G_like; RNA recognition motif in eukaryotic translation initiation factor 3 subunit G (eIF-3G) and similar proteins