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    Ccdc93 coiled-coil domain containing 93 [ Mus musculus (house mouse) ]

    Gene ID: 70829, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ccdc93provided by MGI
    Official Full Name
    coiled-coil domain containing 93provided by MGI
    Primary source
    MGI:MGI:1918079
    See related
    Ensembl:ENSMUSG00000026339 AllianceGenome:MGI:1918079
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4633402D15Rik; 9230102M16Rik
    Summary
    Predicted to be involved in Golgi to plasma membrane transport and endocytic recycling. Predicted to be located in intracellular membrane-bounded organelle. Is expressed in adrenal gland; adrenal medulla; diencephalon; and midbrain floor plate. Orthologous to human CCDC93 (coiled-coil domain containing 93). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 6.5), thymus adult (RPKM 6.3) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ccdc93 in Genome Data Viewer
    Location:
    1 E2.3; 1 52.97 cM
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (121358796..121434189)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (121431067..121506460)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2210011K15 gene Neighboring gene STARR-seq mESC enhancer starr_02075 Neighboring gene STARR-positive B cell enhancer ABC_E10030 Neighboring gene predicted gene, 35243 Neighboring gene 5-hydroxytryptamine (serotonin) receptor 5B Neighboring gene STARR-seq mESC enhancer starr_02076 Neighboring gene DEAD box helicase 18

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane transport  
    involved_in Golgi to plasma membrane transport  
    involved_in Golgi to plasma membrane transport  
    involved_in endocytic recycling  
    involved_in endocytic recycling  
    involved_in protein transport  
    Component Evidence Code Pubs
    located_in early endosome  
    located_in intracellular membrane-bounded organelle  

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 93

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025156.2NP_001020327.1  coiled-coil domain-containing protein 93 isoform a

      See identical proteins and their annotated locations for NP_001020327.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
      Source sequence(s)
      AC111011, BC054083, BY136404, CO042243
      Consensus CDS
      CCDS15237.1
      UniProtKB/Swiss-Prot
      Q3TX53, Q7TQK5
      UniProtKB/TrEMBL
      Q8BUE0
      Related
      ENSMUSP00000043442.10, ENSMUST00000036025.16
      Conserved Domains (2) summary
      pfam09762
      Location:29206
      KOG2701; Coiled-coil domain-containing protein (DUF2037)
      cl12013
      Location:241426
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    2. NM_029955.3NP_084231.2  coiled-coil domain-containing protein 93 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice site in the mid-coding region, compared to variant 1, resulting in a protein (isoform c) that is one amino acid shorter than isoform a.
      Source sequence(s)
      AC111011, AK085701, BY136404, CO042243
      Consensus CDS
      CCDS15238.2
      UniProtKB/TrEMBL
      E9QAD4, Q8BUE0
      Related
      ENSMUSP00000108240.2, ENSMUST00000112621.2
      Conserved Domains (2) summary
      pfam09762
      Location:29206
      KOG2701; Coiled-coil domain-containing protein (DUF2037)
      cl12013
      Location:241425
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      121358796..121434189
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

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