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    Rpl34 ribosomal protein L34 [ Mus musculus (house mouse) ]

    Gene ID: 68436, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rpl34provided by MGI
    Official Full Name
    ribosomal protein L34provided by MGI
    Primary source
    MGI:MGI:1915686
    See related
    Ensembl:ENSMUSG00000062006 AllianceGenome:MGI:1915686
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1100001I22Rik
    Summary
    A structural constituent of ribosome. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in cerebral cortex ventricular layer; cortical plate; and embryo. Orthologous to human RPL34 (ribosomal protein L34). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in large intestine adult (RPKM 318.4), placenta adult (RPKM 290.7) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rpl34 in Genome Data Viewer
    Location:
    3 G3; 3 60.55 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (130520476..130524047, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (130726827..130730398, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36373 Neighboring gene STARR-positive B cell enhancer ABC_E4590 Neighboring gene STARR-positive B cell enhancer ABC_E4591 Neighboring gene STARR-positive B cell enhancer ABC_E828 Neighboring gene oligosaccharyltransferase complex subunit (non-catalytic) Neighboring gene STARR-positive B cell enhancer ABC_E1266 Neighboring gene STARR-seq mESC enhancer starr_08989 Neighboring gene predicted gene 43522 Neighboring gene predicted gene, 36443

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Comparative study of human and mouse postsynaptic proteomes finds high compositional conservation and abundance differences for key synaptic proteins. Bayés A, et al. PLoS One, 2012. PMID 23071613, Free PMC Article
    2. Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice. Jiang X, et al. Nat Commun, 2023 Jun 22. PMID 37349316, Free PMC Article
    3. A male germ-cell-specific ribosome controls male fertility. Li H, et al. Nature, 2022 Dec. PMID 36517592
    4. In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics. Distler U, et al. Proteomics, 2014 Nov. PMID 25211037
    5. Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning. Kondrashov N, et al. Cell, 2011 Apr 29. PMID 21529712, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC103270

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in translation at postsynapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in translation at presynapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in postsynapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in presynapse NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in ribosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    large ribosomal subunit protein eL34
    Names
    60S ribosomal protein L34

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005859.4 → NP_001005859.1  large ribosomal subunit protein eL34

      See identical proteins and their annotated locations for NP_001005859.1

      Status: VALIDATED

      Source sequence(s)
      AC154993
      Consensus CDS
      CCDS17841.1
      UniProtKB/Swiss-Prot
      Q497V4, Q9D1R9
      Related
      ENSMUSP00000078092.7, ENSMUST00000079085.11
      Conserved Domains (1) summary
      pfam01199
      Location:1 → 96
      Ribosomal_L34e; Ribosomal protein L34e

    2. NM_001287581.2 → NP_001274510.1  large ribosomal subunit protein eL34

      See identical proteins and their annotated locations for NP_001274510.1

      Status: VALIDATED

      Source sequence(s)
      AC154993
      Consensus CDS
      CCDS17841.1
      UniProtKB/Swiss-Prot
      Q497V4, Q9D1R9
      Related
      ENSMUSP00000142486.2, ENSMUST00000196202.5
      Conserved Domains (1) summary
      pfam01199
      Location:1 → 96
      Ribosomal_L34e; Ribosomal protein L34e

    3. NM_001429093.1 → NP_001416022.1  large ribosomal subunit protein eL34

      Status: VALIDATED

      Source sequence(s)
      AC154993
      UniProtKB/Swiss-Prot
      Q497V4, Q9D1R9

    4. NM_001429094.1 → NP_001416023.1  large ribosomal subunit protein eL34

      Status: VALIDATED

      Source sequence(s)
      AC154993
      UniProtKB/Swiss-Prot
      Q497V4, Q9D1R9

    5. NM_001429095.1 → NP_001416024.1  large ribosomal subunit protein eL34

      Status: VALIDATED

      Source sequence(s)
      AC154993
      UniProtKB/Swiss-Prot
      Q497V4, Q9D1R9

    6. NM_001429096.1 → NP_001416025.1  large ribosomal subunit protein eL34

      Status: VALIDATED

      Source sequence(s)
      AC154993
      UniProtKB/Swiss-Prot
      Q497V4, Q9D1R9

    7. NM_026724.3 → NP_081000.1  large ribosomal subunit protein eL34

      See identical proteins and their annotated locations for NP_081000.1

      Status: VALIDATED

      Source sequence(s)
      AC154993
      Consensus CDS
      CCDS17841.1
      UniProtKB/Swiss-Prot
      Q497V4, Q9D1R9
      Related
      ENSMUSP00000086614.5, ENSMUST00000062601.14
      Conserved Domains (1) summary
      pfam01199
      Location:1 → 96
      Ribosomal_L34e; Ribosomal protein L34e

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      130520476..130524047 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163263.1 → XP_036019156.1  large ribosomal subunit protein eL34 isoform X1

      UniProtKB/Swiss-Prot
      Q497V4, Q9D1R9
      Conserved Domains (1) summary
      pfam01199
      Location:1 → 96
      Ribosomal_L34e; Ribosomal protein L34e
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D1R9.2 GenPept UniProtKB/Swiss-Prot:Q9D1R9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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