Rnf208 ring finger protein 208 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rnf208provided by MGI
Official Full Name: ring finger protein 208provided by MGI
Primary source: MGI:MGI:1916096
See related: Ensembl:ENSMUSG00000044628 AllianceGenome:MGI:1916096
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 1110061N23Rik
Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein autoubiquitination. Predicted to be located in cytosol and nucleoplasm. Is expressed in nervous system and neural retina. Orthologous to human RNF208 (ring finger protein 208). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human all
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Genomic context

Location:: 2 A3; 2 17.1 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (25132941..25134273)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (25242929..25244261)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables ubiquitin protein ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin-protein transferase activity	IEA Inferred from Electronic Annotation more info
enables ubiquitin-protein transferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in protein autoubiquitination	IEA Inferred from Electronic Annotation more info
involved_in protein autoubiquitination	ISO Inferred from Sequence Orthology more info
involved_in protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: RING finger protein 208

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_176834.2 → NP_789804.2 RING finger protein 208

Status: VALIDATED

Source sequence(s)

AK004344, BQ031423, CX206020

Consensus CDS

CCDS15757.2

UniProtKB/Swiss-Prot

A2AI04, B2FDG8, Q8BTC4, Q8K0W3

Related

ENSMUSP00000109995.2, ENSMUST00000114355.2

Conserved Domains (1) summary

cd16559
Location:144 → 197

RING-HC_RNF208; RING finger, HC subclass, found in RING finger protein 208 (RNF208) and similar proteins