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    SEG1 Seg1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855110, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SEG1
    Official Full Name
    Seg1p
    Primary source
    SGD:S000004692
    Locus tag
    YMR086W
    See related
    AllianceGenome:SGD:S000004692; FungiDB:YMR086W; VEuPathDB:YMR086W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in eisosome assembly. Located in eisosome. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SEG1 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (439208..442090)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene putative glutamine--fructose-6-phosphate transaminase Neighboring gene uncharacterized protein Neighboring gene putative ADP-ribose 1''-phosphate phosphatase Neighboring gene Vba1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Formation and stability of eisosomes in the filamentous fungus Ashbya gossypii. Seger S, et al. J Cell Sci, 2011 May 15. PMID 21525038
    2. The arginine transporter Can1 negatively regulates biofilm formation in yeasts. Nishimura A, et al. Front Microbiol, 2024. PMID 38903792, Free PMC Article
    3. Conserved mechanism of Xrn1 regulation by glycolytic flux and protein aggregation. Mondal S, et al. Heliyon, 2024 Oct 15. PMID 39416838, Free PMC Article
    4. Yeast transformation efficiency is enhanced by TORC1- and eisosome-dependent signaling. Yu SC, et al. Microbiologyopen, 2019 May. PMID 30311441, Free PMC Article
    5. Selection of genes repressed by cAMP that are induced by nutritional limitation in Saccharomyces cerevisiae. Tadi D, et al. Yeast, 1999 Dec. PMID 10590462

    See all (47) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in eisosome assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in cytoplasm HDA PubMed 
    located_in eisosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Seg1p
    NP_013803.1
    • Component of eisosome required for proper eisosome assembly; precedes Pil1p/Lsp1p during eisosome formation, controls eisosome length and shape; diffusely distributed, forms heterogeneous patches at plasma membrane in small buds, also found in medium and large buds; expression repressed by cAMP; similar to A. gossypii SEG gene and to S. pombe Sle1p, important for generating eisosomes; SEG1 has a paralog, SEG2, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      439208..442090
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182586.1 → NP_013803.1  TPA: Seg1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013803.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZQ9, Q04279, Q6B304
      UniProtKB/TrEMBL
      C7GL40
      Conserved Domains (1) summary
      PTZ00341
      Location:215 → 541
      PTZ00341; Ring-infected erythrocyte surface antigen; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04279.1

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