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    brms1 BRMS1 transcriptional repressor and anoikis regulator [ Danio rerio (zebrafish) ]

    Gene ID: 791681, updated on 4-Jan-2025

    Summary

    Official Symbol
    brms1provided by ZNC
    Official Full Name
    BRMS1 transcriptional repressor and anoikis regulatorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030616-596
    See related
    Ensembl:ENSDARG00000051955 AllianceGenome:ZFIN:ZDB-GENE-030616-596
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56414; wu:fb57b08; si:zc194c5.2; si:zc188c22.3
    Summary
    Predicted to enable histone deacetylase binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of Sin3-type complex. Is expressed in telencephalon. Orthologous to human BRMS1 (BRMS1 transcriptional repressor and anoikis regulator). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See brms1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (60396957..60416095)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (60091720..60110858)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496230 Neighboring gene phospholipase C, beta 3 (phosphatidylinositol-specific) Neighboring gene protein phosphatase 1, regulatory (inhibitor) subunit 14Bb Neighboring gene uncharacterized LOC110439982 Neighboring gene pyruvate carboxylase b Neighboring gene leucine-rich repeat and fibronectin type-III domain-containing protein 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC56414

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables histone deacetylase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of Sin3-type complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    breast cancer metastasis-suppressor 1
    Names
    breast cancer metastasis suppressor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200097.1NP_956391.1  breast cancer metastasis-suppressor 1

      See identical proteins and their annotated locations for NP_956391.1

      Status: PROVISIONAL

      Source sequence(s)
      BC049431
      UniProtKB/TrEMBL
      Q7ZWF8
      Related
      ENSDARP00000112377.2, ENSDART00000121545.3
      Conserved Domains (1) summary
      pfam08598
      Location:85253
      Sds3; Sds3-like

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      60396957..60416095
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)