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    flp-22 SPSAKWMRF-amide 3 [ Caenorhabditis elegans ]

    Gene ID: 172665, updated on 9-Dec-2024

    Summary

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    Official Symbol
    flp-22
    Official Full Name
    SPSAKWMRF-amide 3
    Primary source
    WormBase:WBGene00009562
    Locus tag
    CELE_F39H2.1
    See related
    AllianceGenome:WB:WBGene00009562
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables neuropeptide receptor binding activity. Involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Is expressed in neurons and uv1. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See flp-22 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (8658899..8659967)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene t-SNARE coiled-coil homology domain-containing protein Neighboring gene Peptidyl-prolyl cis-trans isomerase sig-7 Neighboring gene 5' exonuclease Apollo Neighboring gene Synaptonemal complex protein 3 Neighboring gene Aminomethyltransferase folate-binding domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FMRFamide-related neuropeptide gene family in Caenorhabditis elegans. Li C, et al. Brain Res, 1999 Nov 27. PMID 10612695
    2. FMRFamide related peptide ligands activate the Caenorhabditis elegans orphan GPCR Y59H11AL.1. Mertens I, et al. Peptides, 2006 Jun. PMID 16377032
    3. Presynaptic coupling by electrical synapses coordinates a rhythmic behavior by synchronizing the activities of a neuron pair. Choi U, et al. Proc Natl Acad Sci U S A, 2021 May 18. PMID 33972428, Free PMC Article
    4. The ovijector of Ascaris suum: multiple response types revealed by Caenorhabditis elegans FMRFamide-related peptides. Moffett CL, et al. Int J Parasitol, 2003 Jul 30. PMID 12865086
    5. Peptidomics of Caenorhabditis elegans: in search of neuropeptides. Husson SJ, et al. Commun Agric Appl Biol Sci, 2005. PMID 16366296

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables neuropeptide receptor binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in neuropeptide signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    SPSAKWMRF-amide 3
    NP_492344.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      8658899..8659967
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059943.8 → NP_492344.2  SPSAKWMRF-amide 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492344.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93702
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q93702.2

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